Glutaredoxin 2 Antibody, ALEXA FLUOR 555
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Catalog number
bs-13394R-A555
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Price
Please ask
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Size
100ul
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Long name
Glutaredoxin 2 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
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Also known as
Anti-Glutaredoxin 2 PAb ALEXA FLUOR 555
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 555
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
Glutaredoxin 2
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Specificity
This is a highly specific antibody against Glutaredoxin 2.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
120-164/164
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Subcellular location
Nucleus, Mitochondrion
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glutaredoxin 2
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Gene ID Number
51022
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Swiss Prot
Q9NS18
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
553nm/568nm
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Synonyms
GRX2; CGI-133; Glutaredoxin-2, mitochondrial; GLRX2
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Properties
For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 555
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French translation
anticorps
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Gene target
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Gene symbol
GLRX2, GLRXP2, GRXCR2
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Short name
Anti-Glutaredoxin 2
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 555
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Alternative name
Glutaredoxin 2 Polyclonal Antibody, ALEXA FLUOR 555
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
glutaredoxin 2
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Synonyms gene name
- glutaredoxin (thioltransferase) 2
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-08-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Glutaredoxin domain containing
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VEGA ID
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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