Recombinant Rat REG3A Protein (His tag)

#

• Catalog number
  PKSR030284-50µg
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• Size
  50µg

# #

• Synonym
  REG3A;Pap2;Reg3
• Activity
  NA
• Sequence
  Met1-Gln174
• Fusion tag
  C-His
• Accession
  BAA04904.1
• ExpressedHost
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 95 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  17.9 kDa
• AP Mol Mass
  17 KDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein which contains one C-type lectin domain. REG3A is constitutively expressed in intestine, and is a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It is overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. REG3A is also a stress protein involved in the control of bacterial proliferation. REG3A is down-regulated in most primary human gastric cancer cells, and might be useful in the diagnosis of gastric cancer. Additionally, REG3A is a target of beta-catenin signaling in Huh7 hepatoma cells. The REG1A and REG3A are downstream targets of the Wnt pathway during liver tumorigenesis.
• Technical data
• Conjugation
  histidine
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

#

• Gene target
  REG3A   Protein   His   tag  
• Gene symbol
  REG3A
• Short name
  Recombinant REG3A Protein (His tag)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  Rat
• Label
  His
• Species
  Rat, Rats
• Alternative name
  Rec. Rat regenerating islet-derived 3 alpha Protein (histidine detection labelled)
• Alternative technique
  rec
• Alternative to gene target
  regenerating islet-derived 3 alpha, HIP and HIP/PAP and INGAP and PAP and PAP-H and PAP1 and PBCGF and REG-III and REG3, REG3A and IDBG-58484 and ENSG00000172016 and 5068, carbohydrate binding, Extracellular

Gene info

• Identity
  HGNC:8601
• Gene
  REG3A
• Long gene name
  regenerating family member 3 alpha
• Synonyms gene
  • PAP
• Synonyms gene name
  • pancreatitis-associated protein
  • regenerating islet-derived 3 alpha
• Synonyms
  • HIP
  • REG-III
  • REG3
  • PBCGF
  • PAP1
• GenBank acession
  • S51768
• Locus
  2p12
• Discovery year
  1993-09-20
• Entrez gene record
  5068
• Pubmed identfication
  • 8188210
• RefSeq identity
  • NM_002580
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000130017

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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