GSK-2018682
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Catalog numberB1967-25
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PricePlease ask
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Size25 mg
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Alternative_name4-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl)-1H-indol-1-yl)butanoic acid
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DescriptionGSK-2018682 is a potent sphingosine -1 phosphate receptor (S1PR)-1 agonist; useful for the treatment of multiple sclerosis. GSK-2018682 induces acute, transient and non-symptomatic decreases in heart rate and blood pressure.
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CAS Number1034688-30-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₂H₂₁ClN₄O₄
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Molecular Weight440.88
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent sphingosine 1 phosphate receptor (S1PR)-1 agonist
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID24988201
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SMILESCC(C)OC1=C(C=C(C=N1)C2=NC(=NO2)C3=C4C=CN(C4=CC=C3)CCCC(=O)O)Cl
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InChiInChI=1S/C22H21ClN4O4/c1-13(2)30-22-17(23)11-14(12-24-22)21-25-20(26-31-21)16-5-3-6-18-15(16)8-10-27(18)9-4-7-19(28)29/h3,5-6,8,10-13H,4,7,9H2,1-2H3,(H,28,29)
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InChi KeyNFIGDBFIDKDNIG-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameGSK-2018682
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Alternative nameGSK-2018682
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