Human CellExp™ BMP-7, Human Recombinant

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• Catalog number
  6446-50
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• Size
  50 ug

# #

• Synonyms
  Osteogenic Protein 1, BMP-7
• Description
  A protein involved in the transformation of mesenchymal cells into bone and cartilage
• Recombinant
  1
• Source
  Human 293 cell expressed
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per 1 ug of protein
• Biological activity
  ED₅₀ is typically 50 to 250 ng/mL. The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).
• Results
  50 to 250 ng/ml
• Molecular Weight
  30 to 38 kDa, homodimer, glycosylated.
• Storage Temp
  -80°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from a solution of 50 mM sodium acetate, pH 4.5, with 50 mM NaCl.
• Reconstitution Instructions
  Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

#

• Gene target
  CellExp™   BMP-7  
• Gene symbol
  BMP7-AS1, BMP7, GDF11, GDF10, PIRC34, PIRC33, BMP1, GDF2, PIRC32, SNORD114-7
• Short name
  CellExp™ BMP-7, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ BMP-7, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:40096
• Gene
  BMP7-AS1
• Long gene name
  BMP7 antisense RNA 1
• Locus
  20q13.31
• Discovery year
  2014-08-08
• Entrez gene record
  102723590
• RefSeq identity
  • NR_110631
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000032810

Gene info

• Identity
  HGNC:1074
• Gene
  BMP7
• Long gene name
  bone morphogenetic protein 7
• Synonyms
  • OP-1
• Synonyms name
  • osteogenic protein 1
• Locus
  20q13.31
• Discovery year
  1991-06-05
• Entrez gene record
  655
• Pubmed identfication
  • 1427904
• RefSeq identity
  • NM_001719
• Classification
  • Bone morphogenetic proteins
• VEGA ID
  OTTHUMG00000032812

Gene info

• Identity
  HGNC:4216
• Gene
  GDF11
• Long gene name
  growth differentiation factor 11
• Synonyms
  • BMP-11
  • BMP11
• GenBank acession
  • AF100907
• Locus
  12q13.2
• Discovery year
  1999-12-02
• Entrez gene record
  10220
• Pubmed identfication
  • 15988002
• Classification
  • Transforming growth factor beta superfamily
• VEGA ID
  OTTHUMG00000170188

Gene info

• Identity
  HGNC:4215
• Gene
  GDF10
• Long gene name
  growth differentiation factor 10
• Synonyms
  • BMP-3b
• GenBank acession
  • L42113
• Locus
  10q11.22
• Discovery year
  1997-09-12
• Entrez gene record
  2662
• Pubmed identfication
  • 8679252
• RefSeq identity
  • NM_004962
• Classification
  • Transforming growth factor beta superfamily
• VEGA ID
  OTTHUMG00000188319

Gene info

• Identity
  HGNC:37538
• Gene
  PIRC34
• Long gene name
  piwi-interacting RNA cluster 34
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313890
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37537
• Gene
  PIRC33
• Long gene name
  piwi-interacting RNA cluster 33
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313854
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:1067
• Gene
  BMP1
• Long gene name
  bone morphogenetic protein 1
• Synonyms gene
  • PCOLC
• Synonyms gene name
  • procollagen C-endopeptidase
• Synonyms
  • BMP-1
• Synonyms name
  • procollagen C-endopeptidase
  • tolloid-like
• Locus
  8p21.3
• Discovery year
  1990-06-11
• Entrez gene record
  649
• Pubmed identfication
  • 2004778
• RefSeq identity
  • NM_006132
• Classification
  • Bone morphogenetic proteins
  • Astacins
• VEGA ID
  OTTHUMG00000097761

Gene info

• Identity
  HGNC:4217
• Gene
  GDF2
• Long gene name
  growth differentiation factor 2
• Synonyms
  • BMP-9
  • BMP9
• GenBank acession
  • AF156891
• Locus
  10q11.22
• Discovery year
  1997-09-12
• Entrez gene record
  2658
• Pubmed identfication
  • 10849432
• RefSeq identity
  • NM_016204
• Classification
  • Transforming growth factor beta superfamily
• VEGA ID
  OTTHUMG00000188320

Gene info

• Identity
  HGNC:37536
• Gene
  PIRC32
• Long gene name
  piwi-interacting RNA cluster 32
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313811
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32995
• Gene
  SNORD114-7
• Long gene name
  small nucleolar RNA, C/D box 114-7
• Synonyms
  • 14q(II-7)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767583
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003199.1
• Classification
  • Small nucleolar RNAs, C/D box

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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