Marimastat

• Catalog number
  1790-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide; BB-2516; TA-2516; Marimistat
• Description
  A broad spectrum matrix metalloprotease (MMP) inhibitor with IC₅₀ values of 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively. It covalently binds to the zinc(II) ion in the active site of MMPs, thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
• CAS Number
  154039-60-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₅H₂₉N₃O₅
• Molecular Weight
  331.41
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (100 mM)
• Handling
  Protect from air and moisture
• Tag Line
  A broad spectrum MMP inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  48 months
• MDL Number
  MFCD00866242
• PubChem CID
  119031
• PubChem CID Link
• SMILES
  CC(C)CC(C(C(=O)NO)O)C(=O)NC(C(=O)NC)C(C)(C)C
• InChi
  InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1
• InChi Key
  OCSMOTCMPXTDND-OUAUKWLOSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Marimastat  
• Short name
  Marimastat
• Alternative name
  Marimastat

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