Ro 20-1724,PDE4 inhibitor

• Catalog number
  SIH-527-250MG
• Price
  Please ask
• Size
  250 mg

• Research Area s
  Cell signaling
• Category
  Small Molecules
• Product Type
  Inhibitor
• CAS No
  29925-17-5
• MolecularFormula
  C15H22N2O3
• Molecular Weight
  278.3
• Purity
  >98% (TLC); NMR (Conforms)
• Solubility
  Soluble in DMSO (200 mg/ml) or ethanol (40 mg/ml)
• Appearance
  White powder
• Storage Temperature
  -20°C
• Shipping Temperature
  Shipped Ambient
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  20-1724   PDE4   inhibitor  
• Gene symbol
  PIRC104, PIRC103, SNORD115-20, SNORD114-20, SNORD116-20, IGKV3-20, IGLVI-20
• Short name
  Ro 20-1724 PDE4 inhibitor
• Alternative name
  Ro 20-1724,PDE4 suppressor

Gene info

• Identity
  HGNC:37608
• Gene
  PIRC104
• Long gene name
  piwi-interacting RNA cluster 104
• Locus
  20
• Discovery year
  2009-11-05
• Entrez gene record
  100313801
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37607
• Gene
  PIRC103
• Long gene name
  piwi-interacting RNA cluster 103
• Locus
  20
• Discovery year
  2009-11-05
• Entrez gene record
  100313901
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33039
• Gene
  SNORD115-20
• Long gene name
  small nucleolar RNA, C/D box 115-20
• Synonyms
  • HBII-52-20
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033460
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003312.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33008
• Gene
  SNORD114-20
• Long gene name
  small nucleolar RNA, C/D box 114-20
• Synonyms
  • 14q(II-20)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767598
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003213.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33086
• Gene
  SNORD116-20
• Long gene name
  small nucleolar RNA, C/D box 116-20
• Synonyms
  • HBII-85-20
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033431
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003334
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5817
• Gene
  IGKV3-20
• Long gene name
  immunoglobulin kappa variable 3-20
• GenBank acession
  • X12686
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28912
• RefSeq identity
  • NG_000834
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151639

Gene info

• Identity
  HGNC:5934
• Gene
  IGLVI-20
• Long gene name
  immunoglobulin lambda variable (I)-20 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable (I)-20
  • immunoglobulin lambda variable (I)-20 pseudogene
• Synonyms
  • IGLV(I)-20
• GenBank acession
  • D87007
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28769
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151242

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