LY-310762 hydrochloride

Alternative_name

1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one hydrochloride
Description

LY-310762 is a potent antagonist of the serotonin (5-HT) receptor subtype 5-HT1D (Ki = 249 nM for guinea pig receptors). It is selective for 5-HT1D over the 5-HT1B receptor, where it inhibits binding of radiolabeled citalopram by only 32% when used at a concentration of 1,000 nM.
CAS Number

192927-92-7
Structure Available

Yes
Salt Form

No
Molecular Formula

C₂₄H₂₇FN₂O₂.HCl
Molecular Weight

430.9
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

DMSO
Handling

Protect from air and light
Tag Line

A potent serotonin (5-HT) receptor subtype 5-HT1D antagonist
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
PubChem CID

11957576
PubChem CID Link
SMILES

CC1(C2=CC=CC=C2N(C1=O)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F)C.Cl
InChi

InChI=1S/C24H27FN2O2.ClH/c1-24(2)20-5-3-4-6-21(20)27(23(24)29)16-15-26-13-11-18(12-14-26)22(28)17-7-9-19(25)10-8-17;/h3-10,18H,11-16H2,1-2H3;1H
InChi Key

BOCLFQZPFYNVFD-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes