RKI-1313

  • Catalog number
    B1092-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    1-(3-Methoxybenzyl)-3-[4-(pyridin-4-yl)thiazol-2-yl]urea
  • Description
    RKI-1313 weak inhibitor for ROCK2-dependent signaling and has less effect on phosphorylation levels of ROCK substrates. RKI-1313 serves as a negative control for RKI-1447 (Cat. No. 2472) which is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.
  • CAS Number
    1342276-76-9
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₇H₁₆N₄O₂S
  • Molecular Weight
    340.4
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A useful negative control for RKI-1447 (Cat.No. 2472)
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    53492330
  • SMILES
    COC1=CC=CC(=C1)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3
  • InChi
    InChI=1S/C17H16N4O2S/c1-23-14-4-2-3-12(9-14)10-19-16(22)21-17-20-15(11-24-17)13-5-7-18-8-6-13/h2-9,11H,10H2,1H3,(H2,19,20,21,22)
  • InChi Key
    BDCUKYUIVYKXCQ-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    RKI-1313
  • Alternative name
    RKI-1313
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