RKI-1313
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Catalog numberB1092-25
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PricePlease ask
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Size25 mg
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Alternative_name1-(3-Methoxybenzyl)-3-[4-(pyridin-4-yl)thiazol-2-yl]urea
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DescriptionRKI-1313 weak inhibitor for ROCK2-dependent signaling and has less effect on phosphorylation levels of ROCK substrates. RKI-1313 serves as a negative control for RKI-1447 (Cat. No. 2472) which is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.
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CAS Number1342276-76-9
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₇H₁₆N₄O₂S
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Molecular Weight340.4
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA useful negative control for RKI-1447 (Cat.No. 2472)
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID53492330
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SMILESCOC1=CC=CC(=C1)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3
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InChiInChI=1S/C17H16N4O2S/c1-23-14-4-2-3-12(9-14)10-19-16(22)21-17-20-15(11-24-17)13-5-7-18-8-6-13/h2-9,11H,10H2,1H3,(H2,19,20,21,22)
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InChi KeyBDCUKYUIVYKXCQ-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameRKI-1313
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Alternative nameRKI-1313
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