anti- PEX5 antibody

• Catalog number
  FNab06331
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
• Immunogen
  peroxisomal biogenesis factor 5
• Synonyms
  FLJ50634, FLJ50721, FLJ51948, Peroxin 5, Peroxisome receptor 1, PEX5, PTS1 BP, PTS1 receptor, PTS1R, PXR1
• Calculated MW
  70 kDa
• Uniprot ID
  P50542
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab06331( PEX5 Antibody) at dilution of 1:200
• Image4
  human brain tissue were subjected to SDS PAGE followed by western blot with FNab06331(PEX5 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PEX5  
• Gene symbol
  PEX5
• Short name
  anti- PEX5 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- PEX5 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9719
• Gene
  PEX5
• Long gene name
  peroxisomal biogenesis factor 5
• Synonyms gene
  • PXR1
• Synonyms gene name
  • peroxisome receptor 1
• Synonyms
  • PTS1R
• Synonyms name
  • peroxisomal targeting signal 1 receptor
  • peroxisomal import receptor 5
• GenBank acession
  • U19721
• Locus
  12p13.31
• Discovery year
  1994-12-13
• Entrez gene record
  5830
• RefSeq identity
  • NM_000319
• Classification
  • Peroxins
  • Tetratricopeptide repeat domain containing
• VEGA ID
  OTTHUMG00000168175
• Locus Specific Databases
  • dbPEX, PEX Gene Database

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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