Anti-Synaptojanin 2, ALEXA Fluor 594

• Catalog number
  GENTObs-11377R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  Synaptojanin 2
• Specificity
  This antibody reacts specifically with Synaptojanin 2
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic peptide derived from human Synaptojanin 2
• Gene ID
  8871
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  5-trisphosphate 5-phosphatase 2; Inositol phosphate 5' phosphatase 2; INPP 5H; INPP5H; KIAA0348; MGC44422; SJ2; Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 2; Synaptic inositol-1; Synaptojanin-2; Synaptojanin2; SYNJ 2; Synj2; SYNJ2_HUMAN.
• Also known as
  Synaptojanin 2 Antibody
• Other name
  Anti-Synaptojanin 2
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  Synaptojanin  
• Gene symbol
  SYNJ2BP, SYNJ2
• Short name
  Anti-Synaptojanin 2
• Technique
  anti-, anti, antibody to, antibodies
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  Synaptojanin 2 Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18955
• Gene
  SYNJ2BP
• Long gene name
  synaptojanin 2 binding protein
• Synonyms
  • Arip2
• Synonyms name
  • activin receptor interacting protein 5
• GenBank acession
  • AK002133
• Locus
  14q24.2
• Discovery year
  2002-07-19
• Entrez gene record
  55333
• Pubmed identfication
  • 11882656
• RefSeq identity
  • NM_018373
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000171240

Gene info

• Identity
  HGNC:11504
• Gene
  SYNJ2
• Long gene name
  synaptojanin 2
• Synonyms
  • INPP5H
• Synonyms name
  • synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2
  • phosphoinositide 5-phosphatase
  • inositol polyphosphate-5-phosphatase H
• GenBank acession
  • AB002346
• Locus
  6q25.3
• Discovery year
  1999-10-14
• Entrez gene record
  8871
• Pubmed identfication
  • 23076136
• RefSeq identity
  • NM_003898
• Classification
  • Phosphoinositide phosphatases
• VEGA ID
  OTTHUMG00000015904

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Product files

Similar products