NU6102

  • Catalog number
    2313-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    O6-Cyclohexylmethyl-2-(4-sulfamoylanilino)purine; 4-​[[6-​(cyclohexylmethoxy)-​9H-​purin-​2-​yl]amino]-​benzenesulfonamide
  • Description
    A potent inhibitor of CDK1 and CDK2 with Ki values of 9 and 6 nM and IC₅₀ values of 9.5 and 5.4 nM, respectively. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC₅₀ = 1.6 μM), DYRK1A (IC₅₀ = 0.9 μM), PDK1 (IC₅₀ = 0.8 μM) and ROCK-II (IC₅₀ = 0.6 μM). Inhibits cell growth.
  • CAS Number
    444722-95-6
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₈H₂₂N₆O₃S
  • Molecular Weight
    402.47
  • Cell Permeable
    Yes
  • Purity
    ≥98% by NMR
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent CDK1 and CDK2 inhibitor
  • Storage Condition
    -20 ̊C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    4566
  • SMILES
    C1CCC(CC1)COC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)S(=O)(=O)N
  • InChi
    InChI=1S/C18H22N6O3S/c19-28(25,26)14-8-6-13(7-9-14)22-18-23-16-15(20-11-21-16)17(24-18)27-10-12-4-2-1-3-5-12/h6-9,11-12H,1-5,10H2,(H2,19,25,26)(H2,20,21,22,23,24)
  • InChi Key
    OWXORKPNCHJYOF-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    NU6102  
  • Short name
    NU6102
  • Alternative name
    NU6102
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