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Form
liquid
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Purification
Immunogen affinity purified
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Purity
≥95% as determined by SDS-PAGE
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Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
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Immunogen
proteasome (prosome, macropain) 26S subunit, ATPase, 6
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Synonyms
SUG2
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Calculated MW
45 kDa
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Uniprot ID
P62333
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Specificity
Human, Mouse, Rat
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Tested Application
ELISA, WB, IHC
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Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
PSMC6
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Short name
anti- PSMC6 antibody
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Technique
Antibody, anti, antibody to, antibodies against human proteins, antibodies for
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Host
Rabbit
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Isotype
IgG
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Alternative name
antibody to- proteasome (prosome, macropain) 26S subunit, ATPase, 6 (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
proteasome (prosome, macropain) 26S subunit, ATPase, 6, CADP44 and HEL-S-73 and p42 and P44 and SUG2, PSMC6 and IDBG-6838 and ENSG00000100519 and 5706, protein binding, nuclei, Psmc6 and IDBG-153111 and ENSMUSG00000021832 and 67089, BT.22570 and IDBG-645288 and ENSBTAG00000015732 and 518637
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