Exemestane

• Catalog number
  9473-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  6-​methylene-​androsta-​1,​4-​diene-​3,​17-​dione
• Description
  Exemestane is a potent, irreversible steroidal aromatase inhibitor (Ki = 10.2 nM; Kinact = 26 nM). It induces aromatase degradation leading to a decrease in estrogen levels in plasma. As an androgen analog, exemestane displays androgenic effects and has been shown to decrease total and HDL cholesterol, apo A1, and total triglyceride levels.
• CAS Number
  107868-30-4
• Structure Available
  Yes
• Molecular Formula
  C₂₀H₂₄O₂
• Molecular Weight
  296.4
• Cell Permeable
  Yes
• Purity
  ≥95%
• Solubilities
  DMSO (30 mg/ml) or EtOH (20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, irreversible steroidal aromatase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00866994
• PubChem CID
  60198
• PubChem CID Link
• SMILES
  CC12CCC3C(C1CCC2=O)CC(=C)C4=CC(=O)C=CC34C
• InChi
  InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
• InChi Key
  FYIZQONLCFLEV-DAELLWKTSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Exemestane  
• Short name
  Exemestane
• Alternative name
  Exemestane

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