Disulfiram

  • Catalog number
    2308-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane;Tetraethylthiuram disulfide; is(diethylthiocarbamyoyl)disulfide
  • Description
    An alcohol dehydrogenase inhibitor used for the treatment of chronic alcoholism. Suppresses the invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression. Also inhibits JMJD2A, a 2-oxoglutarate dependent N(epsilon)-methyl lysine histone demethylase, by disruption of its Zn-binding site.
  • CAS Number
    97-77-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₀H₂₀N₂S₄
  • Molecular Weight
    296.54
  • Cell Permeable
    Yes
  • Purity
    ≥97% by titration
  • Solubilities
    DMSO (~ 6 mg/ml) or Ethanol (~ 30 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    An alcohol dehydrogenase inhibitor
  • Storage Condition
    -20 ̊C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MCFD00009048
  • PubChem CID
    3117
  • SMILES
    CCN(CC)C(=S)SSC(=S)N(CC)CC
  • InChi
    InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
  • InChi Key
    AUZONCFQVSMFAP-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Disulfiram
  • Alternative name
    Disulfiram
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