PU-WS13

• Catalog number
  9442-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
• Description
  PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-WS13 has been shown to reduce the viability of breast cancer cells that express high levels of cell surface HER2 and the viability of human multiple myeloma cells in vitro.
• CAS Number
  1454619-14-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₇H₂₀Cl₂N₆S
• Molecular Weight
  411.35
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  71660551
• PubChem CID Link
• SMILES
  CC(C)NCCCN1C2=C(C(=NC=N2)N)N=C1SC3=CC(=CC(=C3)Cl)Cl
• InChi
  InChI=1S/C17H20Cl2N6S/c1-10(2)21-4-3-5-25-16-14(15(20)22-9-23-16)24-17(25)26-13-7-11(18)6-12(19)8-13/h6-10,21H,3-5H2,1-2H3,(H2,20,22,23)
• InChi Key
  JYSLFQTWNRYWJT-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  PU-WS13  
• Gene symbol
  SPI1
• Short name
  PU-WS13
• Alternative name
  PU-WS13

Gene info

• Identity
  HGNC:11241
• Gene
  SPI1
• Long gene name
  Spi-1 proto-oncogene
• Synonyms gene name
  • spleen focus forming virus (SFFV) proviral integration oncogene
• Synonyms
  • PU.1
  • SPI-A
  • OF
  • SFPI1
  • SPI-1
• Synonyms name
  • hematopoietic transcription factor PU.1
  • 31 kDa transforming protein
• GenBank acession
  • X52056
• Locus
  11p11.2
• Discovery year
  1988-07-04
• Entrez gene record
  6688
• Pubmed identfication
  • 1693183
• RefSeq identity
  • NM_003120
• Classification
  • ETS transcription factor family
• VEGA ID
  OTTHUMG00000150150

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