DMOG

• Catalog number
  2216-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
• Description
  A cell-permeable prolyl 4-hydroxylase (P4H) inhibitor; inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1α; promotes cell survival under hypoxic conditions. DMOG posseses neuroprotective effect on NFG deprived cell cultures through preservation of glucose metabolism. DMOG also attenuates myocardial injury in a rabbit ischemia reperfusion model.
• CAS Number
  89464-63-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₆H₉NO₅
• Molecular Weight
  175.14
• Cell Permeable
  Yes
• Purity
  ³98% by NMR
• Solubilities
  DMSO (100 mM) or H₂O (100 mM)
• Handling
  Protect from light and moisture
• Tag Line
  A hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24months
• MDL Number
  MFCD05865098
• PubChem CID
  560326
• PubChem CID Link
• SMILES
  COC(=O)CNC(=O)C(=O)OC
• InChi
  InChI=1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h3H2,1-2H3,(H,7,9)
• InChi Key
  BNJOZDZCRHCODO-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  DMOG  
• Short name
  DMOG
• Alternative name
  DMOG

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