Factor IX Antibody, ALEXA FLUOR 350

• Catalog number
  bs-9500R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  Factor IX Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-Factor IX PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Factor IX
• Specificity
  This is a highly specific antibody against Factor IX.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Coagulation factor IXa heavy chain
• Gene ID Number
  2158
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and factors X, IX, V, and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble fibrin clots and the promotion of platelet aggregation (1-3). Coagulation factor IX (plasma thromboplastic component, F9, F.IX, HEMB) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor (3,4). Factor XIa mediated proteolytic cleavage of factor IX generates factor IXa, an active serine protease composed of a 145 amino acid light chain and a 236 amino acid catalytic heavy chain, linked through disulfide bonds (5). Genetic alterations at the Factor IX locus such as point mutations, insertions and deletions, can lead to hemophilia B, also known as Christmas disease (6).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  Christmas Disease; Christmas factor; Coagulant factor IX; Coagulation factor 9; Coagulation factor IX plasma thromboplastic component; Coagulation factor IX; Coagulation factor IXa heavy chain; F9; FA9_HUMAN; Factor 9; Factor IX Deficiency; Factor9; FactorIX; FIX; GLA domain; Haemophilia B; MGC129641; MGC129642; P19 antibody Plasma thromboplastic component; Plasma thromboplastin component; PTC; Truncated coagulation factor IX.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• French translation
  anticorps

• Gene target
  Factor  
• Gene symbol
  F9, COX10
• Short name
  Anti-Factor IX
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  Factor IX Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3551
• Gene
  F9
• Long gene name
  coagulation factor IX
• Synonyms
  • FIX
• Synonyms name
  • Factor IX
  • plasma thromboplastic component
  • Christmas disease
  • hemophilia B
• GenBank acession
  • M11309
• Locus
  Xq27.1
• Discovery year
  2001-06-22
• Entrez gene record
  2158
• Classification
  • Gla domain containing
• VEGA ID
  OTTHUMG00000022536
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_556

Gene info

• Identity
  HGNC:2260
• Gene
  COX10
• Long gene name
  cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
• Synonyms gene name
  • COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
  • cytochrome c oxidase assembly homolog 10 (yeast)
  • COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor
• Synonyms name
  • protoheme IX farnesyltransferase, mitochondrial
  • heme O synthase
• GenBank acession
  • U09466
• Locus
  17p12
• Discovery year
  1996-10-31
• Entrez gene record
  1352
• Pubmed identfication
  • 9177788
  • 12928484
• RefSeq identity
  • NM_001303
• Classification
  • Mitochondrial respiratory chain complex assembly factors
• VEGA ID
  OTTHUMG00000058814

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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