GDC0994
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Catalog numberB1629-5
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PricePlease ask
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Size5 mg
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Alternative_nameGDC0994; GDC 0994; GDC-0994; Ravoxertinib; RG7842; RG-7842; RG 7842; 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one
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DescriptionGDC-0994 is highly selective inhibitor of extracellular signal-regulated kinase (ERK), ERK1 and ERK2, with biochemical potency of 1.1 nM and 0.3 nM, respectively.
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CAS Number1453848-26-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₁H₁₈ClFN₆O₂
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Molecular Weight440.86
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA selective inhibitor of ERK1 and ERK2
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD28143918
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PubChem CID71727581
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SMILESCN1C(=CC=N1)NC2=NC=CC(=N2)C3=CC(=O)N(C=C3)C(CO)C4=CC(=C(C=C4)Cl)F
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InChi1S/C21H18ClFN6O2/c1-28-19(5-8-25-28)27-21-24-7-4-17(26-21)13-6-9-29(20(31)11-13)18(12-30)14-2-3-15(22)16(23)10-14/h2-11,18,30H,12H2,1H3,(H,24,26,27)/t18-/m1/s1
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InChi KeyRZUOCXOYPYGSKL-GOSISDBHSA-N
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MSDS AvailableYes
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Gene target
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Short nameGDC0994
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Alternative nameGDC0994
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