GDC0994

  • Catalog number
    B1629-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    GDC0994; GDC 0994; GDC-0994; Ravoxertinib; RG7842; RG-7842; RG 7842; 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one
  • Description
    GDC-0994 is highly selective inhibitor of extracellular signal-regulated kinase (ERK), ERK1 and ERK2, with biochemical potency of 1.1 nM and 0.3 nM, respectively.
  • CAS Number
    1453848-26-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₁H₁₈ClFN₆O₂
  • Molecular Weight
    440.86
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A selective inhibitor of ERK1 and ERK2
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD28143918
  • PubChem CID
    71727581
  • SMILES
    CN1C(=CC=N1)NC2=NC=CC(=N2)C3=CC(=O)N(C=C3)C(CO)C4=CC(=C(C=C4)Cl)F
  • InChi
    1S/C21H18ClFN6O2/c1-28-19(5-8-25-28)27-21-24-7-4-17(26-21)13-6-9-29(20(31)11-13)18(12-30)14-2-3-15(22)16(23)10-14/h2-11,18,30H,12H2,1H3,(H,24,26,27)/t18-/m1/s1
  • InChi Key
    RZUOCXOYPYGSKL-GOSISDBHSA-N
  • MSDS Available
    Yes
  • Gene target
    GDC0994  
  • Short name
    GDC0994
  • Alternative name
    GDC0994
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