(βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate

• Catalog number
  C367615
• Price
  Please ask
• Size
  5 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Pending QC
• Cas number
  681490-92-6
• Chemical s molecular weight
  313.72
• Chemical s main applications
  (βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
• Chemical s category
  Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Chemical s formula
  C8H12ClN3O6S
• Physical properties
  Off White Solid
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  Chloroform, DCM
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications
• Description
  A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

• Gene target
  2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol   1-Methanesulfonate  
• Gene symbol
  VSIR, IGHV7-4-1, TRV-CAC1-4, TRQ-CTG1-4, TRG-GCC1-4, TRL-CAG1-4, TRH-GTG1-4, TRE-CTC1-4, TRUND-NNN4-1, TRV-AAC4-1
• Short name
  (βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate
• Alternative name
  (βR)-2-Chloro-β-hydroxy-β-methyl-4-nitro-1H-imidazole-1-propanol 1-Methanesulfonate

Gene info

• Identity
  HGNC:30085
• Gene
  VSIR
• Long gene name
  V-set immunoregulatory receptor
• Synonyms gene
  • C10orf54
• Synonyms gene name
  • chromosome 10 open reading frame 54
• Synonyms
  • SISP1
  • GI24
  • B7-H5
  • B7H5
  • VISTA
  • PD-1H
  • Dies1
• Synonyms name
  • stress induced secreted protein 1
  • V-domain Ig suppressor of T cell activation
  • PDCD1 homolog
• GenBank acession
  • AF193048
• Locus
  10q22.1
• Discovery year
  2005-10-06
• Entrez gene record
  64115
• Pubmed identfication
  • 12975309
  • 24691993
  • 25279955
• RefSeq identity
  • NM_022153
• Classification
  • B7 family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000018426

Gene info

• Identity
  HGNC:5665
• Gene
  IGHV7-4-1
• Long gene name
  immunoglobulin heavy variable 7-4-1
• GenBank acession
  • L10057
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  57289
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000191141

Gene info

• Identity
  HGNC:34541
• Gene
  TRV-CAC1-4
• Long gene name
  tRNA-Val (anticodon CAC) 1-4
• Synonyms gene
  • TRNAV4
• Synonyms gene name
  • transfer RNA valine 4 (anticodon CAC)
  • transfer RNA-Val (CAC) 1-4
• Synonyms
  • tRNA-Val-CAC-1-4
• GenBank acession
  • HG984114
• Locus
  5q35.3
• Discovery year
  2008-08-27
• Entrez gene record
  100189541
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34884
• Gene
  TRQ-CTG1-4
• Long gene name
  tRNA-Gln (anticodon CTG) 1-4
• Synonyms gene
  • TRNAQ24
  • TRQ-CTG1-1
• Synonyms gene name
  • transfer RNA glutamine 24 (anticodon CUG)
  • transfer RNA-Gln (CTG) 1-1
  • transfer RNA-Gln (CTG) 1-4
• Synonyms
  • tRNA-Gln-CTG-1-4
• GenBank acession
  • HG983716
• Locus
  15q22.31
• Discovery year
  2008-08-29
• Entrez gene record
  100189317
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34722
• Gene
  TRG-GCC1-4
• Long gene name
  tRNA-Gly (anticodon GCC) 1-4
• Synonyms gene
  • TRNAG15
• Synonyms gene name
  • transfer RNA glycine 15 (anticodon GCC)
  • transfer RNA-Gly (GCC) 1-4
• Synonyms
  • tRNA-Gly-GCC-1-4
• GenBank acession
  • HG983809
• Locus
  1q23.3
• Discovery year
  2008-08-29
• Entrez gene record
  100189160
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34932
• Gene
  TRL-CAG1-4
• Long gene name
  tRNA-Leu (anticodon CAG) 1-4
• Synonyms gene
  • TRNAL35
• Synonyms gene name
  • transfer RNA leucine 35 (anticodon CAG)
  • transfer RNA-Leu (CAG) 1-4
• Synonyms
  • tRNA-Leu-CAG-1-4
• GenBank acession
  • HG983892
• Locus
  1q23.3
• Discovery year
  2008-08-29
• Entrez gene record
  100189364
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34736
• Gene
  TRH-GTG1-4
• Long gene name
  tRNA-His (anticodon GTG) 1-4
• Synonyms gene
  • TRNAH7
• Synonyms gene name
  • transfer RNA histidine 7 (anticodon GUG)
  • transfer RNA-His (GTG) 1-4
• Synonyms
  • tRNA-His-GTG-1-4
• GenBank acession
  • HG983835
• Locus
  1q21.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189174
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34822
• Gene
  TRE-CTC1-4
• Long gene name
  tRNA-Glu (anticodon CTC) 1-4
• Synonyms gene
  • TRNAE18
• Synonyms gene name
  • transfer RNA glutamic acid 18 (anticodon CUC)
  • transfer RNA-Glu (CTC) 1-4
• Synonyms
  • tRNA-Glu-CTC-1-4
• GenBank acession
  • HG983756
• Locus
  1q23.3
• Discovery year
  2008-08-29
• Entrez gene record
  100189259
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:50816
• Gene
  TRUND-NNN4-1
• Long gene name
  tRNA-undetermined (NNN) 4-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 4-1
• Synonyms
  • tRNA-Und-NNN-4-1
• GenBank acession
  • HG984093
• Locus
  1p36.23
• Discovery year
  2014-06-20
• Entrez gene record
  103482530
• Pubmed identfication
  • 18984615
• Classification
  • Cytoplasmic transfer RNA pseudogenes

Gene info

• Identity
  HGNC:34723
• Gene
  TRV-AAC4-1
• Long gene name
  tRNA-Val (anticodon AAC) 4-1
• Synonyms gene
  • TRNAV17
• Synonyms gene name
  • transfer RNA valine 17 (anticodon AAC)
  • transfer RNA-Val (AAC) 4-1
• Synonyms
  • tRNA-Val-AAC-4-1
• GenBank acession
  • HG984107
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189161
• Classification
  • Cytoplasmic transfer RNAs

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