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HEXA Beta hexosaminidase subunit alpha Antibody ALEXA FLUOR

HEXA Beta hexosaminidase subunit alpha Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-11726R-A350 | HEXA/Beta hexosaminidase subunit alpha Antibody, ALEXA FLUOR 350 size: 100ul | 441.94 USD

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bs-11726R-A488 | HEXA/Beta hexosaminidase subunit alpha Antibody, ALEXA FLUOR 488 size: 100ul | 441.94 USD

Catalog number bs-11726R-A488
Price 441.94 USD
Size 100ul
Long name HEXA/Beta hexosaminidase subunit alpha Antibody, ALEXA FLUOR 488 Conjugated
Also known as Anti-HEXA/Beta hexosaminidase subunit alpha PAb ALEXA FLUOR 488
Conjugated with ALEXA FLUOR® 488
Excitation emission 499nm/519nm
Properties For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-HEXA/Beta hexosaminidase subunit alpha has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation Alexa Fluor
Description The Anti-HEXA/Beta hexosaminidase subunit alpha is a α- or alpha protein sometimes glycoprotein present in blood.
French translation anticorps
Label ALEXA FLUOR 488
Alternative name HEXA/Beta hexosaminidase subunit alpha Antibody, ALEXA FLUOR 488
1. Gene info
Identity 4878
Gene HEXA
Long gene name hexosaminidase subunit alpha
Synonyms gene name
  • hexosaminidase A (alpha polypeptide)
Synonyms name
  • Tay Sachs disease
  • GM2 gangliosidosis
  • beta-hexosaminidase subunit alpha
GenBank acession
  • M13520
Locus 15q23
Discovery year 2001-06-22
Entrez gene record 3073
Pubmed identfication
  • 2952641
  • 3013851
RefSeq identity
  • NM_000520
Classification
  • Hexosaminidases
Havana BLAST/BLAT OTTHUMG00000133445
Locus Specific Databases
  • Hexosaminidase A; Tay-Sachs Disease
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database
Product images
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Product files

bs-11726R-A555 | HEXA/Beta hexosaminidase subunit alpha Antibody, ALEXA FLUOR 555 size: 100ul | 441.94 USD

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bs-11726R-A594 | HEXA/Beta hexosaminidase subunit alpha Antibody, ALEXA FLUOR 594 size: 100ul | 441.94 USD

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bs-11726R-A647 | HEXA/Beta hexosaminidase subunit alpha Antibody, ALEXA FLUOR 647 size: 100ul | 441.94 USD

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Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen HEXA/Beta hexosaminidase subunit alpha
Specificity This is a highly specific antibody against HEXA/Beta hexosaminidase subunit alpha.
Modification Unmodified
Modification Site None
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Beta hexosaminidase subunit alpha
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human, Mouse, Rat
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Synonyms Beta hexosaminidase alpha chain precursor; Beta hexosaminidase subunit alpha; Beta N acetylhexosaminidase; Beta N acetylhexosaminidase subunit alpha; Beta-hexosaminidase subunit alpha; Beta-N-acetylhexosaminidase subunit alpha; Hexa; HEXA_HUMAN; Hexosaminidase A alpha polypeptide; Hexosaminidase A alpha polypeptide; Hexosaminidase A; Hexosaminidase subunit A; MGC99608; N acetyl beta glucosaminidase; N acetyl beta glucosaminidase subunit alpha; N-acetyl-beta-glucosaminidase subunit alpha; TSD.
Gene targetHEXA/Beta hexosaminidase subunit alpha
Short name Anti-HEXA/Beta hexosaminidase subunit alpha
Technique Antibody
Isotype Immunoglobulin G (IgG)
Alternative technique antibodies
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Anti-HEXA/Beta hexosaminidase subunit alpha | Technique alte
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  • HEXA/Beta
  • hexosaminidase
  • subunit
  • alpha
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