XEN445

• Catalog number
  2681-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (S)-2-(3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid
• Description
  XEN445 is a potent and selective endothelial lipase (EL) inhibitor. It displays good ADME and PK properties and shows in vivo efficacy in raising plasma HDL cholesterol concentration in mice.
• CAS Number
  1515856-92-4
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₁₈H₁₇F₃N₂O₃
• Molecular Weight
  366.33
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent and selective endothelial lipase (EL) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• SMILES
  O=C(O)C1=CC(C(F)(F)F)=CC=C1N2C[C@@H](OCC3=NC=CC=C3)CC2
• InChi
  InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1
• InChi Key
  NBGRERFNOKZQLO-AWEZNQCLSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  XEN445  
• Short name
  XEN445
• Alternative name
  XEN445

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