StemRegenin 1
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Catalog number1967-5
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PricePlease ask
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Size5 mg
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Alternative_name4-(2-((2-Benzo[b]thiphen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol hydrochloride; SR2
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DescriptionA cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs). Culture of HSCs with SR1 led to a 50-fold increase in cells expressing CD34 and a 17-fold increase in cells that retain the ability to engraft immunodeficient mice. In the absence of cytokines, StemRegenin 1 did not induce proliferation, and at concentrations above 1 µM, it inhibits proliferation.
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₄H₂₃N₅OS.HCl
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Molecular Weight466
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~ 10 mM)
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HandlingProtect from light and air
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Tag LineA promoter of self-renewal of hematopoietic stem cells (HSCs)
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life48 months
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SMILESN/A
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InChiN/A
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InChi KeyN/A
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MSDS AvailableYes
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Gene target
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Short nameStemRegenin 1
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Alternative nameStemRegenin 1
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