StemRegenin 1

  • Catalog number
    1967-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    4-(2-((2-Benzo[b]thiphen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol hydrochloride; SR2
  • Description
    A cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs). Culture of HSCs with SR1 led to a 50-fold increase in cells expressing CD34 and a 17-fold increase in cells that retain the ability to engraft immunodeficient mice. In the absence of cytokines, StemRegenin 1 did not induce proliferation, and at concentrations above 1 µM, it inhibits proliferation.
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₄H₂₃N₅OS.HCl
  • Molecular Weight
    466
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~ 10 mM)
  • Handling
    Protect from light and air
  • Tag Line
    A promoter of self-renewal of hematopoietic stem cells (HSCs)
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    48 months
  • SMILES
    N/A
  • InChi
    N/A
  • InChi Key
    N/A
  • MSDS Available
    Yes
  • Gene target
  • Short name
    StemRegenin 1
  • Alternative name
    StemRegenin 1
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