Iberdomide

• Catalog number
  B2284-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione; CC-220
• Description
  Iberdomide is a celebron modulator that displays an IC₅₀ of 60 nM in TR-FRET cereblon binding assay. Cereblon is a substrate receptor in the CRL4 ubiquitin ligase complex. Iberdomide is potentially useful for the treatment of systemic lupus erythematosus (SLE), an autoimmune disease that is characterized by production of autoantibodies.
• CAS Number
  1323403-33-3
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₅H₂₇N₃O₅
• Molecular Weight
  449.5
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A celebron modulator
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  67335295
• PubChem CID Link
• SMILES
  C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3OCC4=CC=C(C=C4)CN5CCOCC5
• InChi
  InChI=1S/C25H27N3O5/c29-23-9-8-21(24(30)26-23)28-15-20-19(25(28)31)2-1-3-22(20)33-16-18-6-4-17(5-7-18)14-27-10-12-32-13-11-27/h1-7,21H,8-16H2,(H,26,29,30)/t21-/m0/s1
• InChi Key
  IXZOHGPZAQLIBH-NRFANRHFSA-N
• Data Sheet Link
• MSDS Available
  YES

• Gene target
  Iberdomide  
• Short name
  Iberdomide
• Alternative name
  Iberdomide

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