DNA Polymerase Kappa/POLK Antibody

• Catalog number
  bs-13019R
• Price
  Please ask
• Size
  0.1ml

• Long name
  DNA Polymerase Kappa/POLK Antibody
• Also known as
  DNA Polymerase Kappa/POLK Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  DNA Polymerase Kappa/POLK
• Specificity
  This is a highly specific antibody against DNA Polymerase Kappa/POLK.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK
• Gene ID number
  51426
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  DNA polymerase lambda (pol Kappa), also designated DNA polymerase Kappa or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol Kappa is a member of the DNA polymerase type-X family. Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol Kappa may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  DNA polymerase kappa; DINB protein; Short=DINP; POLK_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DNA   Polymerase   Kappa/POLK  
• Gene symbol
  POLK, PRKDC, HLA-DOA, TENT4A
• Short name
  Anti-DNA Polymerase Kappa/POLK
• Technique
  Antibody, dna, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  DNA Polymerase Kappa/POLK Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9183
• Gene
  POLK
• Long gene name
  DNA polymerase kappa
• Synonyms gene
  • DINB1
• Synonyms gene name
  • polymerase (DNA directed) kappa
  • polymerase (DNA) kappa
• Synonyms
  • POLQ
  • DINP
• Synonyms name
  • DINB protein
  • DNA polymerase kappa
• GenBank acession
  • AB027564
• Locus
  5q13.3
• Discovery year
  2000-08-11
• Entrez gene record
  51426
• Pubmed identfication
  • 10887153
  • 10518552
• RefSeq identity
  • NM_016218
• Classification
  • DNA polymerases
• VEGA ID
  OTTHUMG00000102107

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:16705
• Gene
  TENT4A
• Long gene name
  terminal nucleotidyltransferase 4A
• Synonyms gene
  • POLS
  • PAPD7
• Synonyms gene name
  • polymerase (DNA directed) sigma
  • PAP associated domain containing 7
  • poly(A) RNA polymerase D7, non-canonical
• Synonyms
  • POLK
  • TRF4
  • LAK-1
  • TRF4-1
• Synonyms name
  • topoisomerase-related function protein 4-1
  • polymerase (DNA-directed) sigma
  • DNA polymerase kappa
  • TUTase5
• GenBank acession
  • AF089896
• Locus
  5p15.31
• Discovery year
  2001-09-27
• Entrez gene record
  11044
• Pubmed identfication
  • 10066793
  • 10926539
  • 23376078
• RefSeq identity
  • NM_006999
• Classification
  • Terminal nucleotidyltransferases
  • Non-canonical poly(A) polymerases
• VEGA ID
  OTTHUMG00000090457

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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