Ac-DEVD-CHO
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Catalog numberB1951-5
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PricePlease ask
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Size5 mg
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Alternative_nameAc-Asp-Glu-Val-Asp-CHO; caspase-3 inhibitor
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DescriptionAc-DEVD-CHO is a potent and reversible inhibitor of the Group II caspases, caspase-3 and caspase-7 (Ki's = 0.23 and 1.6 nM, respectively). The DEVD sequence is based on PARP cleavage site Asp-216 for caspase-3.
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CAS Number169332-60-9
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Structure AvailableYes
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Peptide sequenceAc-Asp-Glu-Val-Asp-CHO
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Salt FormNo
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Molecular FormulaC₂₀H₃₀N₄O₁₁
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Molecular Weight502.48
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>25 mg/ml)
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HandlingProtect from air and moisture
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Tag LineA reversible caspase-3 inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD00671412
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PubChem CID644345
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SMILESCC(C)C(C(=O)NC(CC(=O)O)C=O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C
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InChiInChI=1S/C20H30N4O11/c1-9(2)17(20(35)22-11(8-25)6-15(29)30)24-18(33)12(4-5-14(27)28)23-19(34)13(7-16(31)32)21-10(3)26/h8-9,11-13,17H,4
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InChi KeyUMBVAPCONCILTL-MRHIQRDNSA-N
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MSDS AvailableYes
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Gene target
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Short nameAc-DEVD-CHO
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Hostcho
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Alternative nameAc-DEVD-CHO
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