Caspase 3, Pro, Active/Cleaved (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein) Antibody

• Catalog number
  MBS646981
• Price
  Please ask
• Size
  0.05 ml

• Alternative name1
  Anti-Caspase 3, Pro, Active/Cleaved (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein)
• Alternative name2
  Caspase 3, Pro, Active/Cleaved (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein)
• Alternative name3
  Caspase 3, Pro, Active/Cleaved (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein)
• Alternative name4
  Caspase 3, Pro, Active/Cleaved
• Alternative name5
  Anti -Caspase 3, Pro, Active/Cleaved (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein)
• Other names
  caspase-5 isoform f; Caspase-5; caspase-5; CASP-5; TY protease; protease TY; ICE(rel)-III; protease ICH-3; caspase 5, apoptosis-related cysteine protease; caspase 5, apoptosis-related cysteine peptidase; ICE(rel)-III; Protease ICH-3; Protease TY
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  CASP5; CASP5; ICH-3; ICEREL-III; ICE(rel)III; ICH3; CASP-5
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  IgG
• Clone
  Polyclonal antibody
• Host organism
  Host: Rabbit; Source: Human
• Species reactivity
  Canine, Human, Mouse, Rat
• Specificity and cross reactivity
  Recognizes the proform of human caspase-3 (~32kD), and the large (~14-21kD) and small (~10kD) subunits of active/cleaved Caspase-3. Species Crossreactivity: canine, gerbil, mouse, rat.
• Purification method
  Serum
• Form Appearance
  Supplied as a liquid, 0.05% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store at 4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested for
  Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional description
  This 1 is suited for programmed cell-death studies. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
• Gene
  Cys or cysteines ChEMBL54943
• French translation
  anticorps

• Gene target
  Caspase   Pro   Active/Cleaved   Caspase-3   CASP   CASP3   CASP-3   CPP-32   Apopain   Yama   SCA-1   ASP3   related   Cysteine   Peptidase   Apopain   Apopain   Cysteine   Protease   CPP32   SREBP   Cleavage   Activity   Yama   Yama   Protein  
• Gene symbol
  CASP3, CRTAP, CYTIP, CASP8, CPP, LY6E, MILR1, IGKV1D-32, CUX1, SNORD115-32
• Short name
  Caspase 3, Pro, Active/Cleaved (Caspase-3, CASP 3, CASP3, CASP-3, CPP-32, Apopain, Yama, SCA-1, ASP3, Apoptosis- Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein) Antibody
• Technique
  apoptosis, Antibody, antibodies against human proteins, antibodies for, apoptosis pathway
• Alternative name
  caspase 3, L-proline, functionnal/Cleaved (caspase-3, caspase 3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, CPP-32, Apopain, Yama, SCA-1, ASP3, programmed cellular destruction-related Cysteine Peptidase Apopain, Apopain, Cysteine Protease CPP32, SREBP Cleavage Activity 1, Yama, Yama Protein) (antibody to-)
• Alternative technique
  celldeath, antibodies
• Alternative to gene target
  caspase 3, apoptosis-related cysteine peptidase, CPP32 and CPP32B and SCA-1, CASP3 and IDBG-46394 and ENSG00000164305 and 836, cysteine-type endopeptidase activity involved in execution phase of apoptosis, nuclei, Casp3 and IDBG-154306 and ENSMUSG00000031628 and 12367, CASP3 and IDBG-628521 and ENSBTAG00000015874 and 408016

Gene info

• Identity
  HGNC:1504
• Gene
  CASP3
• Long gene name
  caspase 3
• Synonyms gene name
  • caspase 3, apoptosis-related cysteine protease
  • caspase 3, apoptosis-related cysteine peptidase
• Synonyms
  • CPP32
  • CPP32B
  • Yama
  • apopain
• GenBank acession
  • BC016926
• Locus
  4q35.1
• Discovery year
  1996-07-22
• Entrez gene record
  836
• Pubmed identfication
  • 8780721
• RefSeq identity
  • NM_004346
• Classification
  • Caspases
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000133681

Gene info

• Identity
  HGNC:2379
• Gene
  CRTAP
• Long gene name
  cartilage associated protein
• Synonyms
  • CASP
  • LEPREL3
  • P3H5
• Synonyms name
  • leprecan-like 3
  • prolyl 3-hydroxylase family member 5 (non-enzymatic)
• GenBank acession
  • AJ006470
• Locus
  3p22.3
• Discovery year
  1999-10-19
• Entrez gene record
  10491
• Pubmed identfication
  • 9217321
  • 10429950
• Classification
  • Prolyl 3-hydroxylase family
• VEGA ID
  OTTHUMG00000130746
• Locus Specific Databases
  • Osteogenesis Imperfecta Variant Database
  • LRG_4

Gene info

• Identity
  HGNC:9506
• Gene
  CYTIP
• Long gene name
  cytohesin 1 interacting protein
• Synonyms gene
  • PSCDBP
• Synonyms gene name
  • pleckstrin homology, Sec7 and coiled-coil domains, binding protein
• Synonyms
  • B3-1
  • HE
  • CYBR
  • CASP
  • CYTHIP
• Synonyms name
  • cytohesin binding protein HE
  • cytohesin binder and regulator
• GenBank acession
  • L06633
• Locus
  2q24.1
• Discovery year
  1999-07-19
• Entrez gene record
  9595
• Pubmed identfication
  • 18926288
  • 10343115
  • 11867758
  • 20530790
  • 21562043
• RefSeq identity
  • NM_004288
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000154551

Gene info

• Identity
  HGNC:1509
• Gene
  CASP8
• Long gene name
  caspase 8
• Synonyms gene name
  • caspase 8, apoptosis-related cysteine protease
  • caspase 8, apoptosis-related cysteine peptidase
• Synonyms
  • MCH5
  • MACH
  • FLICE
  • Casp-8
• GenBank acession
  • U60520
• Locus
  2q33.1
• Discovery year
  1996-11-11
• Entrez gene record
  841
• Pubmed identfication
  • 8681376
  • 8681377
• RefSeq identity
  • NM_001228
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132821
• Locus Specific Databases
  • CASP8base: Mutation registry for Caspase 8 deficiency
  • LRG_34

Gene info

• Identity
  HGNC:2322
• Gene
  CPP
• Long gene name
  ceruloplasmin pseudogene
• Synonyms gene name
  • ceruloplasmin (ferroxidase) pseudogene
• GenBank acession
  • M18058
• Locus
  8q21.3
• Discovery year
  2001-06-22
• Entrez gene record
  340451
• Pubmed identfication
  • 3427102
• RefSeq identity
  • NG_001106

Gene info

• Identity
  HGNC:6727
• Gene
  LY6E
• Long gene name
  lymphocyte antigen 6 family member E
• Synonyms gene name
  • lymphocyte antigen 6 complex, locus E
• Synonyms
  • TSA-1
  • RIG-E
  • SCA-2
• Synonyms name
  • retinoic acid induced gene E
• GenBank acession
  • U42376
• Locus
  8q24.3
• Discovery year
  1998-06-19
• Entrez gene record
  4061
• Pubmed identfication
  • 8757598
  • 8650192
• RefSeq identity
  • NM_001127213
• Classification
  • LY6/PLAUR domain containing
• VEGA ID
  OTTHUMG00000164754

Gene info

• Identity
  HGNC:27570
• Gene
  MILR1
• Long gene name
  mast cell immunoglobulin like receptor 1
• Synonyms gene
  • C17orf60
• Synonyms gene name
  • chromosome 17 open reading frame 60
  • mast cell immunoglobulin-like receptor 1
• Synonyms
  • Allergin-1
  • MCA-32
• Synonyms name
  • allergy inhibitory receptor 1
  • mast cell antigen 32
• GenBank acession
  • BC053534
• Locus
  17q23.3
• Discovery year
  2005-12-16
• Entrez gene record
  284021
• Pubmed identfication
  • 20526344
• RefSeq identity
  • NM_001085423
• Classification
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000185198

Gene info

• Identity
  HGNC:5752
• Gene
  IGKV1D-32
• Long gene name
  immunoglobulin kappa variable 1D-32 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 1D-32
• GenBank acession
  • X71896
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28897
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151614

Gene info

• Identity
  HGNC:2557
• Gene
  CUX1
• Long gene name
  cut like homeobox 1
• Synonyms gene
  • CUTL1
• Synonyms gene name
  • cut (Drosophila)-like 1 (CCAAT displacement protein)
  • cut-like 1, CCAAT displacement protein (Drosophila)
  • cut-like homeobox 1
• Synonyms
  • CDP
  • CDP1
  • CUX
  • CUT
  • Clox
  • CDP/Cut
  • CDP/Cux
  • Cux/CDP
  • CASP
  • GOLIM6
• Synonyms name
  • golgi integral membrane protein 6
  • CUX1 gene Alternatively Spliced Product
• GenBank acession
  • M74099
• Locus
  7q22.1
• Discovery year
  1992-12-13
• Entrez gene record
  1523
• Pubmed identfication
  • 8468066
  • 9799793
  • 15004235
• RefSeq identity
  • NM_001913
• Classification
  • Golgins
  • CUT class homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000157129
• Locus Specific Databases
  • LRG_1123

Gene info

• Identity
  HGNC:33051
• Gene
  SNORD115-32
• Long gene name
  small nucleolar RNA, C/D box 115-32
• Synonyms
  • HBII-52-32
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033806
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003347.1
• Classification
  • Small nucleolar RNAs, C/D box

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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