Kevetrin hydrochloride
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Catalog numberB1068-50
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PricePlease ask
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Size50 mg
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Alternative_name3-cyanopropyl carbamimidothioate hydrochloride
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DescriptionKevetrin is a water-soluble, small molecule activator of the tumor suppressor protein p53, with potential antineoplastic activity. p53 functions by activating proteins that repair DNA and kill cells that have genetic mutations such as in cancers. Research experiments show that when cancer cells are treated with Kevetrin, it activates p53 which induces p21, a protein that inhibits cancer cell growth. p53 also induces PUMA (p53 up-regulated modulator of apoptosis), a protein that causes tumor cell death.
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CAS Number66592-89-0
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₅H₁₀ClN₃S
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Molecular Weight179.67
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesH₂O
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HandlingProtect from air and moisture
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Tag LineA water-soluble, small molecule activator of the tumor suppressor protein p53
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID49778916
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SMILESC(CC#N)CSC(=N)N.Cl
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InChiInChI=1S/C5H9N3S.ClH/c6-3-1-2-4-9-5(7)8;/h1-2,4H2,(H3,7,8);1H
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InChi KeyNCXJZJFDQMKRKM-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameKevetrin hydrochloride
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Alternative nameKevetrin hydrochloride
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