Kevetrin hydrochloride

  • Catalog number
    B1068-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    3-cyanopropyl carbamimidothioate hydrochloride
  • Description
    Kevetrin is a water-soluble, small molecule activator of the tumor suppressor protein p53, with potential antineoplastic activity. p53 functions by activating proteins that repair DNA and kill cells that have genetic mutations such as in cancers. Research experiments show that when cancer cells are treated with Kevetrin, it activates p53 which induces p21, a protein that inhibits cancer cell growth. p53 also induces PUMA (p53 up-regulated modulator of apoptosis), a protein that causes tumor cell death.
  • CAS Number
    66592-89-0
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₅H₁₀ClN₃S
  • Molecular Weight
    179.67
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    H₂O
  • Handling
    Protect from air and moisture
  • Tag Line
    A water-soluble, small molecule activator of the tumor suppressor protein p53
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    49778916
  • SMILES
    C(CC#N)CSC(=N)N.Cl
  • InChi
    InChI=1S/C5H9N3S.ClH/c6-3-1-2-4-9-5(7)8;/h1-2,4H2,(H3,7,8);1H
  • InChi Key
    NCXJZJFDQMKRKM-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Kevetrin hydrochloride
  • Alternative name
    Kevetrin hydrochloride
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