Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
NCF1/p47 phox Ser359
This is a highly specific antibody against NCF1/p47 phox Ser359.
1ug per 1ul
KLH conjugated synthetic phosphopeptide derived from human NCF1 around the phosphorylation site of Ser359
Gene ID number
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
The heredity chronic granulomatous disease (CGF) has been linked to mutations in p47-phox and p67-phox. The cytosolic proteins p47-phox and p67-phox, also designated neutrophil cytosol factor (NCF)1 and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47-phox and p67-phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67-phox has been shown to interact with the proline-rich domain of p47-phox, suggesting that p47-phox may faciliate the transport of p67-phox to the membrane.
This antibody was purified via Protein A.
NCF1Ser359; p47 phoxSer359; NCF1 phospho S359; 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NCF 47K; Neutrophil cytosol factor 1; Neutrophil cytosolic factor 1; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox organizing protein 2; NOXO2; p47 phox; p47phox; ;SH3 and PX domain containing protein 1A; SH3PXD1A; NADPH oxidase p47 phox; NCF1_HUMAN.
Anti-NCF1/p47 phox Ser359
Immunoglobulin G (IgG)
Alternative to gene target
neutrophil cytosolic factor 1, NCF1 and IDBG-21570 and ENSG00000158517 and 653361, phosphatidylinositol-3, Plasma membranes, Ncf1 and IDBG-202592 and ENSMUSG00000015950 and 17969, NCF1 and IDBG-639883 and ENSBTAG00000003305 and 281345