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Alternative_name
Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl]
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Description
Beauvercin is an enniatin mycotoxin isolated from fungus Beauveria sp. It has shown cytotoxic properties against insect cells SF-9 and induces apoptosis with IC₅₀ value of 4.5 µM. It has shown to affect mitochondria by depleting the transmembrane potential, inducing swelling and decreasing calcium retention capacity.
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CAS Number
26048-05-5
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₄₅H₅₇N₃O₉
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Molecular Weight
783.96
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Cell Permeable
Yes
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Purity
≥97% by HPLC
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Solubilities
DMSO(>19 mg/ml)
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Handling
Protect from air and light
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Tag Line
An enniatin mycotoxin inducing apoptosis and having cytotoxic properties
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
36 months
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MDL Number
MFCD00056846
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PubChem CID
105014
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SMILES
CC(C)C1C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)O1)CC2=CC=CC=C2)C)C(C)C)CC3=CC=CC=C3)C)C(C)C)CC4=CC=CC=C4)C
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InChi
InChI=1S/C45H57N3O9/c1-28(2)37-40(49)46(7)35(26-32-21-15-11-16-22-32)44(53)56-39(30(5)6)42(51)48(9)36(27-33-23-17-12-18-24-33)45(54)57-38(29(3)4)41(50)47(8)34(43(52)55-37)25-31-19-13-10-14-20-31/h10-24,28-30,34-39H,25-27H2,1-9H3
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InChi Key
GYSCAQFHASJXRS-UHFFFAOYSA-N
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MSDS Available
Yes
