Anti-CD20 (Rituximab), Chimeric Antibody

• Catalog number
  A1049-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  CD20
• Target Alternative Name
  MabThra
• Antibody Type
  Monoclonal
• Species Reactivities
  Human
• Immunogen Sequence
  CD20
• Accession
  NP_690605
• Gene Id
  54474
• Appearance
  Colourless liquid
• Form
  Liquid
• Concentration
  2 mg/ml
• Formulation
  100 ug (2 mg/ml) of antibody in Phosphate buffered saline, pH 7.4.
• Purification
  human IgG1 was expressed in a human cell line. IgG was purified from CHO cell culture supernatant by protein A chromatography.
• Application
  Neutralization, ELISA
• Application And Usages
  Activation : 1-20 μg/ml; ELISA: 2μg/ml
• Description
  Rituximab, a chimeric monoclonal antibody targeted against the pan-B-cell marker CD20. Mechanisms of cell destruction that have been demonstrated to be activated by rituximab binding to CD20 include direct signaling of apoptosis, complement activation and antibody dependent cellular cytotoxicity. Rituximab is a mainstay in the therapy for a broad variety of B-cell malignancies.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD20   Rituximab   Chimeric  
• Gene symbol
  MS4A1
• Short name
  Anti-CD20 (Rituximab), Chimeric Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Human IgG1
• Alternative name
  Antibody toCD20 (Rituximab), Chimeric (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7315
• Gene
  MS4A1
• Long gene name
  membrane spanning 4-domains A1
• Synonyms gene
  • CD20
• Synonyms gene name
  • membrane-spanning 4-domains, subfamily A, member 1
• Synonyms
  • B1
  • Bp35
  • FMC7
• GenBank acession
  • M27394
• Locus
  11q12.2
• Discovery year
  1989-05-23
• Entrez gene record
  931
• Pubmed identfication
  • 2448768
• Classification
  • Membrane spanning 4-domains
  • CD molecules
• VEGA ID
  OTTHUMG00000167614
• Locus Specific Databases
  • LRG_140

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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