GSK1278863
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Catalog numberB1107-5
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PricePlease ask
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Size5 mg
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Alternative_name(1, 3-Dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine; Daprodustat
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DescriptionGSK-1278863 is a novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor (HIF-PHI). Hypoxia-inducible factor−prolyl hydroxylase inhibitors stimulate endogenous EPO synthesis and induce effective erythropoiesis by non-EPO effects.
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CAS Number960539-70-2
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Structure AvailableYes
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Salt FormYes
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Molecular FormulaC₁₉H₂₇N₃O₆
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Molecular Weight393.44
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>30 mg/ml)
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HandlingProtect from air and light
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Tag LineA novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID91617630
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SMILESC1CCC(CC1)N2C(=O)C(C(=O)N(C2=O)C3CCCCC3)C(=O)NCC(=O)O
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InChiInChI=1S/C19H27N3O6/c23-14(24)11-20-16(25)15-17(26)21(12-7-3-1-4-8-12)19(28)22(18(15)27)13-9-5-2-6-10-13/h12-13,15H,1-11H2,(H,20,25)(H,23,24)
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InChi KeyRUEYEZADQJCKGV-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameGSK1278863
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Alternative nameGSK1278863
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