Epothilone D

• Catalog number
  9559-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  (4S,7R,8S,9S,16S,Z)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)oxacyclohexadec-13-ene-2,6-dione;  (-)-Desoxyepothilone B; (-)-Epothilone D; 12,13-Deoxyepothilone B; 12,13-Desoxyepothilone B; Desoxyepothilone B; Epo D; Epothilone D; KOS 862; KOS862; KOS-862; NSC 703147
• Description
  Epothilone D is a natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the inhibition of mitosis, cellular proliferation, and cell motility.
• CAS Number
  189453-10-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₇H₄₁NO₅S
• Molecular Weight
  491.68
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>30 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A microtubule stabilizing agent
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  447865
• PubChem CID Link
• SMILES
  CC1CCCC(=CCC(OC(=O)CC(C(C(=O)C(C1O)C)(C)C)O)C(=CC2=CSC(=N2)C)C)C
• InChi
  InChI=1S/C27H41NO5S/c1-16-9-8-10-17(2)25(31)19(4)26(32)27(6,7)23(29)14-24(30)33-22(12-11-16)18(3)13-21-15-34-20(5)28-21/h11,13,15,17,19,22-23,25,29,31H,8-10,12,14H2,1-7H3/b16-11-,18-13+/t17-,19+,22-,23-,25-/m0/s1
• InChi Key
  XOZIUKBZLSUILX-GIQCAXHBSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Epothilone  
• Short name
  Epothilone D
• Alternative name
  Epothilone D

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