CDHF15/FAT3 Antibody, ALEXA FLUOR 350
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Catalog numberbs-11081R-A350
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PricePlease ask
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Size100ul
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Long nameCDHF15/FAT3 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
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Also known asAnti-CDHF15/FAT3 PAb ALEXA FLUOR 350
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 350
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenCDHF15/FAT3
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SpecificityThis is a highly specific antibody against CDHF15/FAT3.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDHF15/FAT3
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Tested applicationsFCM, IF(IHC-P)
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Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenThe cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including ∫-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT3 (FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. Containing thirty-three cadherin domains, four EGF-like domains and one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission343nm/442nm
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SynonymsCadherin family member 15; CDHF15; CDHR10; FAT tumor suppressor homolog 3; Fat3; FAT3_HUMAN; hFat3; Protocadherin Fat 3.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 350
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French translationanticorps
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Gene target
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Gene symbolFAT3
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Short nameAnti-CDHF15/FAT3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 350
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Alternative nameCDHF15/FAT3 Polyclonal Antibody, ALEXA FLUOR 350
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Alternative techniqueantibodies
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Alternative to gene targetFAT tumor suppressor homolog 3 (Drosophila), FAT3 and IDBG-67775 and ENSG00000165323 and 120114, protein binding, Plasma membranes, Fat3 and IDBG-135915 and ENSMUSG00000074505 and 270120, FAT3 and IDBG-641733 and ENSBTAG00000004081 and
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Gene info
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Identity
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Gene
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Long gene nameFAT atypical cadherin 3
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Synonyms gene name
- FAT tumor suppressor homolog 3 (Drosophila)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-09-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Cadherin related
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data