PIAS2, CT (E3 SUMO-protein Ligase PIAS2, Protein Inhibitor of Activated STAT2, Protein Inhibitor of Activated STAT x, Msx-interacting Zinc Finger Protein, Miz1, DAB2-interacting Protein, DIP, Androgen Receptor-interacting Protein 3, ARIP3, PIAS-NY Protein
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Catalog numberMBS626028
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Price:
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Size0.2 mL
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Products_typeAntibody
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Products_short_name[PIAS2]
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Products_name_syn[Anti -PIAS2, CT (E3 SUMO-protein Ligase PIAS2, Protein Inhibitor of Activated STAT2, Protein Inhibitor of Activated STAT x, Msx-interacting Zinc Finger Protein, Miz1, DAB2-interacting Protein, DIP, Androgen Receptor-interacting Protein 3, ARIP3, PIAS-NY Protein]
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Other_names[E3 SUMO-protein ligase PIAS2 isoform X4; protein inhibitor of activated STAT, 2]
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Other_gene_names[PIAS2]
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ClonalityPolyclonal
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ReactivityHuman
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SpecificityRecognizes human PIAS2.
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PurityAffinity Purified Purified by Protein G affinity chromatography.
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FormSupplied as a liquid in PBS, 0.09% sodium azide.
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Storage_stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_applicationELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionFinger like and finger proteins are like zinc fingers small proteins with a structural motif that is characterized by the coordination of one or more zinc ions in order to stabilize the fold. Homeobox and homeodomain families. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.
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Gene target
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Gene symbolPIAS2, DAB2, SUMO1, STAT2, GRAMD4, STAT6, QRICH1, SOAT1, CCDC73, ANKRD30A
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Short namePIAS2, CT (E3 SUMO-protein Ligase PIAS2, Protein Inhibitor of Activated STAT2, Protein Inhibitor of Activated STAT x, Msx-interacting Zinc Finger Protein, Miz1, DAB2-interacting Protein, DIP, Androgen Receptor-interacting Protein 3, ARIP3, PIAS-NY Protein
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HostRabbit
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IsotypeIgG
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Alternative namePIAS2, CT (E3 SUMO-protein Ligase PIAS2, Protein suppressor on Activated signal transducer and activator on transcription 2, 113kDa, Protein suppressor on Activated Signal transducer and activation on transcription x, Msx-interacting Zinc Finger Protein, Miz1, DAB2-interacting Protein, DIP, Androgen Receptor-interacting Protein 3, ARIP3, PIAS-NY Protein
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Alternative to gene targetsignal transducer and activator of transcription 2, 113kDa, ISGF-3 and P113 and STAT113, STAT2 and IDBG-40906 and ENSG00000170581 and 6773, identical protein binding, nuclei, Stat2 and IDBG-197036 and ENSMUSG00000040033 and 20847, STAT2 and IDBG-635999 and ENSBTAG00000004380 and 511023
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Gene info
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Identity
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Gene
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Long gene nameprotein inhibitor of activated STAT 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-06-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers MIZ-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameDAB adaptor protein 2
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Synonyms gene name
- disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)
- disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
- Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
- DAB2, clathrin adaptor protein
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall ubiquitin like modifier 1
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Synonyms gene
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Synonyms gene name
- ubiquitin-like 1 (sentrin)
- SMT3 suppressor of mif two 3 homolog 1 (yeast)
- SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-06-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesignal transducer and activator of transcription 2
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Synonyms gene name
- signal transducer and activator of transcription 2, 113kD
- signal transducer and activator of transcription 2, 113kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-11-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameGRAM domain containing 4
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Synonyms
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Synonyms name
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Locus
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Discovery year2008-03-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- GRAM domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesignal transducer and activator of transcription 6
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Synonyms gene name
- signal transducer and activator of transcription 6, interleukin-4 induced
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-11-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameglutamine rich 1
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Synonyms
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Locus
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Discovery year2005-12-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesterol O-acyltransferase 1
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Synonyms gene
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Synonyms gene name
- sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-11-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecoiled-coil domain containing 73
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-02-11
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Entrez gene record
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameankyrin repeat domain 30A
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-05-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ankyrin repeat domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
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Tree numbers
- E05.393.620.311
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data