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[Anti -PIAS2 (Protein Inhibitor of Activated STAT2, Androgen Receptor-interacting Protein 3, ARIP3, DAB2-interacting Protein, DIP, E3 SUMO Protein Ligase PIAS2, Msx-interacting Zinc Finger Protein, Miz1, PIAS-NY Protein, PIASX, Protein Inhibitor of Activated Sta]
[E3 SUMO-protein ligase PIAS2 isoform X4; protein inhibitor of activated STAT, 2]
Recognizes human PIAS2. Species sequence homology: mouse, rat, canine.
Affinity Purified Purified by peptide affinity chromatography.
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
ELISA (EL/EIA), Immunohistochemistry (IHC)
Finger like and finger proteins are like zinc fingers small proteins with a structural motif that is characterized by the coordination of one or more zinc ions in order to stabilize the fold. Homeobox and homeodomain families.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Alternative to gene target
signal transducer and activator of transcription 2, 113kDa, ISGF-3 and P113 and STAT113, STAT2 and IDBG-40906 and ENSG00000170581 and 6773, identical protein binding, nuclei, Stat2 and IDBG-197036 and ENSMUSG00000040033 and 20847, STAT2 and IDBG-635999 and ENSBTAG00000004380 and 511023