Alternative names of antibody target:
C11, CTLA-1, Cathepsin G-like 1, CGL1, CSPB, CTLA1, GRB
Background information:
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
This antibody reacts with:
Human, mouse, rat
Concentration of antibody:
0.5 mg/ml
Formulation of this antibody:
30 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 50 % glycerol and 0.3 % ProClin®
Purification method:
Affinity Purified Antibody
This antibody has been succesfully tested for use in following methods:
Western blot
Recommended usage:
Western blot: 1-4 µg
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps
Identity 4709
Gene GZMB
Long gene name granzyme B
Synonyms gene name- granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
Synonyms- CCPI
- CGL-1
- CSP-B
- CGL1
- CTSGL1
- HLP
- SECT
Synonyms name- fragmentin 2
- cytotoxic serine protease B
- cathepsin G-like 1
- T-cell serine protease 1-3E
- granzyme 2
- cytotoxic T-lymphocyte-associated serine esterase 1
Locus 14q12
Discovery year 1989-05-12
Entrez gene record 3002
Classification- Granule associated serine proteases of immune defence
Havana BLAST/BLAT OTTHUMG00000029369
