Human CellExp™ CD47, rat recombinant

• Catalog number
  P1076-50
• Price
  Please ask
• Size
  50 µg

• Synonyms
  CD47, MER6, IAP, OA3
• Alternative_names
  CD47, MER6, IAP, OA3
• Description
  Plays a role in cell adhesion modulation of integrins
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  >95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1 EU/ug
• Molecular Weight
  40.4 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
• Reconstitution Instructions
  Reconstitute in sterile deionized water to a concentration of 50 ug/ml.
• Background Information
  Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   CD47  
• Gene symbol
  CD47
• Short name
  CellExp™ CD47, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Rat
• Species
  Humans, Rats
• Alternative name
  H. sapiens CellExp™ CD47 molecule, rat Rec.
• Alternative technique
  rec
• Alternative to gene target
  CD47 molecule, IAP and MER6 and OA3, CD47 and IDBG-48744 and ENSG00000196776 and 961, thrombospondin receptor activity, Plasma membranes, Cd47 and IDBG-165137 and ENSMUSG00000055447 and 16423, CD47 and IDBG-631689 and ENSBTAG00000003585 and 282661

Gene info

• Identity
  HGNC:1682
• Gene
  CD47
• Long gene name
  CD47 molecule
• Synonyms gene
  • MER6
• Synonyms gene name
  • CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
• Synonyms
  • IAP
  • OA3
• Synonyms name
  • antigen identified by monoclonal antibody 1D8
  • antigenic surface determinant protein OA3
  • integrin associated protein
  • Rh-related antigen
  • leukocyte surface antigen CD47
  • CD47 glycoprotein
• Locus
  3q13.12
• Discovery year
  1994-12-12
• Entrez gene record
  961
• Pubmed identfication
  • 8294396
  • 2277087
• RefSeq identity
  • NM_001777
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000044216

MeSH Data

• Name
  CD4 Lymphocyte Count
• Concept
  Scope note: The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
• Tree numbers
  • E01.370.225.500.195.107.595.500.150
  • E01.370.225.625.107.595.500.150
  • E05.200.500.195.107.595.500.150
  • E05.200.625.107.595.500.150
  • E05.242.195.107.595.500.150
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products