NLG919
-
Catalog number9407-5
-
PricePlease ask
-
Size5 mg
-
-
Alternative_name1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol; NLG-919
-
DescriptionNLG919 is a potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway (Ki = 7 nM). Indoleamine 2,3-dioxygenase (IDO) is an enzyme with immune-suppressive properties that is commonly exploited by tumors to evade immune destruction.
-
CAS Number1402836-58-1
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₁₈H₂₂N₂O
-
Molecular Weight282.38
-
Cell PermeableYes
-
Purity≥98% by HPLC
-
SolubilitiesDMSO (~ 3 mg/ml)
-
HandlingProtect from air and light
-
Tag LineA potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway inhibitor
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life36 months
-
PubChem CID66558287
-
SMILESC1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O
-
InChiInChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2
-
InChi KeyYTRRAUACYORZLX-UHFFFAOYSA-N
-
MSDS AvailableYes
-
Gene target
-
Short nameNLG919
-
Alternative nameNLG919
-