Mouse anti V-CAM-1 (CD106)

• Catalog number
  X1474M
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-110). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on unstimulated endothelial cells. It is also present on follicular and interfollicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin 4 1 (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
• Antibody come from
  Synthetic peptide derived from the rat Kv1.1 potassium channel conjugated to KLH
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
• Clone
  1.4C3
• Antigen antibody binding interaction
  Mouse anti V-CAM-1 (CD106) Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Immunohistochemistry
• Antibody s suited for
  This antibody can be used for Western blotting (5-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  1. Baumann,A et.al Structure of the voltage-dependent potassium channel is highly conserved from Drosophila to vertebrate central nervous systems. EMBO J. 7 (8), 2457-2463 (1988)_x000B__x000B_2. Christie,M.J et.al. Expression of a cloned rat brain potassium channel in Xenopus oocytes_x000B_Science 244 (4901), 221-224 (1989)_x000B__x000B_3. Hatton WJ, et.al Functional and molecular expression of a voltage-dependent K(+) channel (Kv1.1) in interstitial cells of Cajal. J Physiol 2001 Jun 1 533:Pt 2 315-27(2001) _x000B__x000B_4. Wang FC et.al alpha subunit compositions of Kv1.1-containing K+ channel subtypes fractionated from rat brain using dendrotoxins. Eur J Biochem Jul 263:1 230-7 (1999)_x000B__x000B_5. Folco E, et.al A cellular model for long QT syndrome. Trapping of heteromultimeric complexes consisting of truncated Kv1.1 potassium channel polypeptides and native Kv1.4 and Kv1.5 channels in the endoplasmic reticulum J Biol Chem Oct 17 272:42 26505-10 (1997) _x000B__x000B_6. Roberds,S.L Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart Proc. Natl. Acad. Sci. U.S.A. 88 (5), 1798-1802 (1991)_x000B_
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  V-CAM-1   CD106  
• Gene symbol
  VCAM1, MTPN, KRIT1, CAMK2N2, GH2, POLH, CFAP251, B4GALT5, CFAP91, IGLVV-66
• Short name
  Mouse anti V-CAM-1 (CD106)
• Technique
  Mouse, anti, antibody to, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to V-CAM-1 (CD106)
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:12663
• Gene
  VCAM1
• Long gene name
  vascular cell adhesion molecule 1
• Synonyms
  • CD106
• GenBank acession
  • M60335
• Locus
  1p21.2
• Discovery year
  1991-07-10
• Entrez gene record
  7412
• RefSeq identity
  • NM_001078
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • Receptor ligands
  • C2-set domain containing
  • I-set domain containing
• VEGA ID
  OTTHUMG00000010982

Gene info

• Identity
  HGNC:15667
• Gene
  MTPN
• Long gene name
  myotrophin
• Synonyms
  • MYOTROPHIN
  • GCDP
  • V-1
• Synonyms name
  • granule cell differentiation protein
• GenBank acession
  • AC015987
• Locus
  7q33
• Discovery year
  2001-08-16
• Entrez gene record
  136319
• Pubmed identfication
  • 11474205
• RefSeq identity
  • NM_145808
• Classification
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000155627

Gene info

• Identity
  HGNC:1573
• Gene
  KRIT1
• Long gene name
  KRIT1 ankyrin repeat containing
• Synonyms gene
  • CCM1
• Synonyms gene name
  • cerebral cavernous malformations 1
  • KRIT1, ankyrin repeat containing
• Synonyms
  • CAM
• GenBank acession
  • AJ294850
• Locus
  7q21.2
• Discovery year
  1995-06-02
• Entrez gene record
  889
• Pubmed identfication
  • 7604043
  • 11342228
• Classification
  • FERM domain containing
  • Ankyrin repeat domain containing
  • CCM adhesion complex
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000131187
• Locus Specific Databases
  • LRG_650

Gene info

• Identity
  HGNC:24197
• Gene
  CAMK2N2
• Long gene name
  calcium/calmodulin dependent protein kinase II inhibitor 2
• Synonyms
  • CaM-KIIN
• GenBank acession
  • AY037149
• Locus
  3q27.1
• Discovery year
  2005-06-10
• Entrez gene record
  94032
• Pubmed identfication
  • 11444830
  • 9724800
• RefSeq identity
  • NM_033259
• VEGA ID
  OTTHUMG00000156821

Gene info

• Identity
  HGNC:4262
• Gene
  GH2
• Long gene name
  growth hormone 2
• Synonyms
  • GH-V
  • GHV
  • GHL
  • hGH-V
• Synonyms name
  • placental-specific growth hormone
  • placenta-specific growth hormone
• GenBank acession
  • J03756
• Locus
  17q23.3
• Discovery year
  2001-06-22
• Entrez gene record
  2689
• Pubmed identfication
  • 6306568
• RefSeq identity
  • NM_002059
• Classification
  • Growth hormone family
• VEGA ID
  OTTHUMG00000172284

Gene info

• Identity
  HGNC:9181
• Gene
  POLH
• Long gene name
  DNA polymerase eta
• Synonyms gene name
  • polymerase (DNA directed), eta
  • polymerase (DNA) eta
• Synonyms
  • RAD30A
  • XP-V
• GenBank acession
  • AB024313
• Locus
  6p21.1
• Discovery year
  1997-09-12
• Entrez gene record
  5429
• Pubmed identfication
  • 20012583
  • 10385124
  • 10398605
• RefSeq identity
  • NM_006502
• Classification
  • DNA polymerases
  • Xeroderma pigmentosum complementation groups
• VEGA ID
  OTTHUMG00000014743
• Locus Specific Databases
  • LRG_470

Gene info

• Identity
  HGNC:28506
• Gene
  CFAP251
• Long gene name
  cilia and flagella associated protein 251
• Synonyms gene
  • WDR66
• Synonyms gene name
  • WD repeat domain 66
• Synonyms
  • MGC33630
  • CaM-IP4
• GenBank acession
  • AL833930
• Locus
  12q24.31
• Discovery year
  2005-05-26
• Entrez gene record
  144406
• Pubmed identfication
  • 17967944
• RefSeq identity
  • NM_144668
• Classification
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000168948

Gene info

• Identity
  HGNC:928
• Gene
  B4GALT5
• Long gene name
  beta-1,4-galactosyltransferase 5
• Synonyms gene name
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
• Synonyms
  • beta4GalT-V
• Synonyms name
  • beta4-GalT IV
• GenBank acession
  • AB004550
• Locus
  20q13.13
• Discovery year
  1999-03-15
• Entrez gene record
  9334
• Pubmed identfication
  • 9597550
  • 9435216
• RefSeq identity
  • NM_004776
• Classification
  • Beta 4-glycosyltransferases
• VEGA ID
  OTTHUMG00000033086

Gene info

• Identity
  HGNC:24010
• Gene
  CFAP91
• Long gene name
  cilia and flagella associated protein 91
• Synonyms gene
  • C3orf15
  • MAATS1
• Synonyms gene name
  • chromosome 3 open reading frame 15
  • MYCBP/AMY-1-associated, testis expressed 1
  • MYCBP-associated, testis expressed 1
  • MYCBP associated and testis expressed 1
• Synonyms
  • AAT1
  • AAT1alpha
  • SPATA26
  • CaM-IP2
  • AAT-1
• Synonyms name
  • AMY-1-associating protein expressed in testis 1
  • MYCBP-binding protein
  • spermatogenesis associated 26
• GenBank acession
  • AB063296
• Locus
  3q13.33
• Discovery year
  2004-07-26
• Entrez gene record
  89876
• Pubmed identfication
  • 12223483
  • 14551891
  • 17967944
• RefSeq identity
  • NM_033364
• VEGA ID
  OTTHUMG00000159422

Gene info

• Identity
  HGNC:5946
• Gene
  IGLVV-66
• Long gene name
  immunoglobulin lambda variable (V)-66 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable (V)-66
  • immunoglobulin lambda variable (V)-66 pseudogene
• Synonyms
  • IGLV(V)-66
• GenBank acession
  • D87004
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28757
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151584

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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