Recombinant Human Activin Receptor 2A/Activin RIIA/ACVR2A (C-Fc-6His)

• Catalog number
  CB60
• Price
  Please ask
• Size
  1mg

• Alternative names
  Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2
• Description
  Recombinant Human Activin Receptor IIA is produced by our Mammalian expression system and the target gene encoding Ala20-Pro134 is expressed with a Fc, 6His tag at the C-terminus.
• Expression
  Human Cells
• Tag
  C-Fc&His
• Endotoxin
  Less than 0.1 ng/ug (1 EU/ug)
• Accession
  P27037
• TargetSequence
  Ala20-Pro134
• Shipping
  Ambient
• Formulation
  Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
• Note
  For research use only.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Activin   Receptor   2A/Activin   RIIA/ACVR2A   C-Fc-6His  
• Gene symbol
  ACVR2A, FCGR2A
• Short name
  Recombinant Activin Receptor 2A/Activin RIIA/ACVR2A (C-Fc-6His)
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Activin Receptor 2A/Activin RIIA/ACVR2A (C-fragment c-6His)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:173
• Gene
  ACVR2A
• Long gene name
  activin A receptor type 2A
• Synonyms gene
  • ACVR2
• Synonyms gene name
  • activin A receptor, type II
  • activin A receptor, type IIA
• Synonyms
  • ACTRII
• Locus
  2q22.3-q23.1
• Discovery year
  1993-09-17
• Entrez gene record
  92
• Pubmed identfication
  • 1314589
  • 10702675
• RefSeq identity
  • NM_001616
• Classification
  • Type 2 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000150603

Gene info

• Identity
  HGNC:3616
• Gene
  FCGR2A
• Long gene name
  Fc gamma receptor IIa
• Synonyms gene
  • FCG2
  • FCGR2A1
  • FCGR2
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
  • Fc fragment of IgG, low affinity IIa, receptor (CD32)
  • Fc fragment of IgG receptor IIa
• Synonyms
  • CD32
  • CD32A
  • IGFR2
  • CDw32
  • Fc-gamma-RIIa
  • FcgammaRIIa
• Synonyms name
  • Immunoglobulin G Fc receptor II
• GenBank acession
  • J03619
• Locus
  1q23.3
• Discovery year
  1988-11-30
• Entrez gene record
  2212
• Pubmed identfication
  • 2139735
  • 8994865
• RefSeq identity
  • NM_021642
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000034469
• Locus Specific Databases
  • LRG_1109

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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