Target of this antibody:
Alternative names of antibody target:
LAMP-3 (lysosome-associated membrane protein-3)
Anti-CD63 recognizes an extracellular fragment of CD63, a 56-kilodalton (kDa), type III lysosomal glycoprotein, belonging to the tetraspanin family. CD63 is expressed by granulocytes, platelets, T-cells, monocytes/macrophages, endothelial cells. CD63 protein is also expressed in exosome membrane. Cell sur-face exposition of CD63 is usually activation dependent. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell co-stimulator molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas.
Clonality of antibody:
T-cell line HRB-ALL
Concentration of antibody:
Formulation of this antibody:
1 mg/ml in phosphate buffered saline (PBS) with sodium azide (15 mM), Approx. pH: 7.4.
Protein A affinity chromatography
This antibody has been succesfully tested for use in following methods:
WB, ELISA, FACS, IP, IHC-frozen, IHC-formalin (antigen retrieval required)
WB (1:1000), ELISA (1:500), FACS (1:200), IP, IHC-frozen, IHC-formalin (antigen retrieval required).
Shelf time: Do not use after expiration date stamped on vial label. in temp.: 4 deg.C
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Biovision supplies antibodies that are for research of human proteins.
anti-Anti- CD63 antibody
anti-Human, Antibody, anti
antibody to-Anti-H. sapiens CD63 molecule (Antibody to)
Alternative to gene target
CD63 molecule, LAMP-3 and ME491 and MLA1 and OMA81H and TSPAN30, CD63 and IDBG-38974 and ENSG00000135404 and 967, protein binding, Cell surfaces, Cd63 and IDBG-198573 and ENSMUSG00000025351 and 12512