Amidepsine A, Humcola sp.

• Catalog number
  2147-1000
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  N-[4-[[4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl]oxy]-2-hydroxy-6-methylbenzoyl]-L-alanine
• Description
  A diacylglycerol acyltransferase (DGAT) inhibitor. Shows inhibitory effect in rat liver microsomes (IC₅₀ = 10.2 µM) and Raji cells (IC₅₀ = 15.5 µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
• CAS Number
  169181-28-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₉H₂₉NO₁₁
• Molecular Weight
  567.55
• Cell Permeable
  Yes
• Purity
  ≥95% by HPLC
• Solubilities
  DMSO or EtOH
• Handling
  Protect from air and light
• Tag Line
  A diacylglycerol acyltransferase (DGAT) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24months
• PubChem CID
  10099481
• PubChem CID Link
• SMILES
  CC1=CC(=CC(=C1C(=O)NC(C)C(=O)O)O)OC(=O)C2=C(C=C(C=C2C)OC(=O)C3=C(C=C(C=C3C)OC)OC)O
• InChi
  InChI=1S/C29H29NO11/c1-13-8-18(10-20(31)23(13)26(33)30-16(4)27(34)35)40-28(36)24-14(2)9-19(11-21(24)32)41-29(37)25-15(3)7-17(38-5)12-22(25)39-6/h7-12,16,31-32H,1-6H3,(H,30,33)(H,34,35)
• InChi Key
  XQGKRCPZJSNFEL-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Amidepsine   Humcola  
• Short name
  Amidepsine A, Humcola sp.
• Alternative name
  Amidepsine A, Humcola sp.

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