Ethynylcytidine

• Catalog number
  B1266-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  1-(3-C-Ethynyl-beta-D-ribo-pentofuranosyl)cytosine; TAS-106
• Description
  Ethynylcytidine is a synthetic cytidine nucleoside containing a covalently bound ethynyl group with potential antineoplastic and radiosensitizing activities. Ethynylcytidine is metabolized in tumor cells to ethynylcytidine triphosphate (ECTP), which inhibits RNA synthesis by competitive inhibition of RNA polymerases I, II and III; subsequently, RNase L is activated, resulting in apoptosis.
• CAS Number
  180300-43-0
• Structure Available
  Yes
• Molecular Formula
  C₁₁H₁₃N₃O₅
• Molecular Weight
  267.24
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  An anticancer agent
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  176885
• PubChem CID Link
• SMILES
  C#CC1(C(OC(C1O)N2C=CC(=NC2=O)N)CO)O
• InChi
  InChI=1S/C11H13N3O5/c1-2-11(18)6(5-15)19-9(8(11)16)14-4-3-7(12)13-10(14)17/h1,3-4,6,8-9,15-16,18H,5H2,(H2,12,13,17)/t6-,8+,9-,11-/m1/s1
• InChi Key
  JFIWEPHGRUDAJN-DYUFWOLASA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Ethynylcytidine  
• Short name
  Ethynylcytidine
• Alternative name
  Ethynylcytidine

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