XMD8-92

• Catalog number
  B1684-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  XMD8-92; XMD 8 92; XMD 892; XMD8-92; XMD8 92; XMD892; 2-[2-ethoxy-4-(4-hydroxypiperidin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one
• Description
  XMD8-92 is a highly selective ERK5/BMK1 inhibitor with dissociation constant (Kd) value of 80 nM.
• CAS Number
  1234480-50-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₃₀N₆O₃
• Molecular Weight
  474.55
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A BMK1/ERK5 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  NA
• PubChem CID
  46843772
• PubChem CID Link
• SMILES
  CCOC1=C(C=CC(=C1)N2CCC(CC2)O)NC3=NC=C4C(=N3)N(C5=CC=CC=C5C(=O)N4C)C
• InChi
  InChI=1S/C26H30N6O3/c1-4-35-23-15-17(32-13-11-18(33)12-14-32)9-10-20(23)28-26-27-16-22-24(29-26)30(2)21-8-6-5-7-19(21)25(34)31(22)3/h5-10,15-16,18,33H,4,11-14H2,1-3H3,(H,27,28,29)
• InChi Key
  QAPAJIZPZGWAND-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  XMD8-92  
• Gene symbol
  COQ4, ZNF154, HLA-L, MIR92A2, MIR92A1, MIR17HG, OR5B1P
• Short name
  XMD8-92
• Alternative name
  XMD8-92

Gene info

• Identity
  HGNC:19693
• Gene
  COQ4
• Long gene name
  coenzyme Q4
• Synonyms gene name
  • coenzyme Q4 homolog (yeast)
  • coenzyme Q4 homolog (S. cerevisiae)
• Synonyms
  • CGI-92
• GenBank acession
  • AF151850
• Locus
  9q34.11
• Discovery year
  2003-01-10
• Entrez gene record
  51117
• Pubmed identfication
  • 11469793
  • 18474229
• RefSeq identity
  • NM_016035
• VEGA ID
  OTTHUMG00000020743

Gene info

• Identity
  HGNC:12939
• Gene
  ZNF154
• Long gene name
  zinc finger protein 154
• Synonyms gene name
  • zinc finger protein 154 (pHZ-92)
• Synonyms
  • pHZ-92
• GenBank acession
  • U20648
• Locus
  19q13.43
• Discovery year
  1994-03-16
• Entrez gene record
  7710
• Pubmed identfication
  • 7557990
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000140375

Gene info

• Identity
  HGNC:4970
• Gene
  HLA-L
• Long gene name
  major histocompatibility complex, class I, L (pseudogene)
• Synonyms gene
  • HLA92
  • HLAL
• Synonyms
  • HLA-92
• GenBank acession
  • M96338
• Locus
  6p22.1
• Discovery year
  1993-11-02
• Entrez gene record
  3139
• Pubmed identfication
  • 1517564
• RefSeq identity
  • NR_027822
• Classification
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031164
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:31644
• Gene
  MIR92A2
• Long gene name
  microRNA 92a-2
• Synonyms gene
  • MIRN92-2
  • MIRN92A2
• Synonyms gene name
  • microRNA 92-2
• Synonyms
  • hsa-mir-92-2
  • hsa-mir-92a-2
• Locus
  Xq26.2
• Discovery year
  2004-04-23
• Entrez gene record
  407049
• RefSeq identity
  • NR_029509
• Classification
  • MicroRNA MIR25/92 family

Gene info

• Identity
  HGNC:31643
• Gene
  MIR92A1
• Long gene name
  microRNA 92a-1
• Synonyms gene
  • MIRN92-1
  • MIRN92A1
• Synonyms gene name
  • microRNA 92-1
• Synonyms
  • hsa-mir-92-1
  • hsa-mir-92a-1
• Locus
  13q31.3
• Discovery year
  2004-04-23
• Entrez gene record
  407048
• RefSeq identity
  • NR_029508
• Classification
  • MicroRNA MIR25/92 family

Gene info

• Identity
  HGNC:23564
• Gene
  MIR17HG
• Long gene name
  miR-17-92a-1 cluster host gene
• Synonyms gene
  • C13orf25
  • MIRHG1
• Synonyms gene name
  • chromosome 13 open reading frame 25
  • microRNA host gene 1 (non-protein coding)
  • MIR17 host gene (non-protein coding)
  • miR-17-92 cluster host gene
• Synonyms
  • FLJ14178
  • MIRH1
  • MIHG1
  • NCRNA00048
  • miR-17-92
  • LINC00048
• Synonyms name
  • non-protein coding RNA 48
  • long intergenic non-protein coding RNA 48
• GenBank acession
  • AB176707
• Locus
  13q31.3
• Discovery year
  2004-07-28
• Entrez gene record
  407975
• Pubmed identfication
  • 15126345
  • 15944707
  • 16266980
  • 17210683
  • 23551855
• RefSeq identity
  • NR_027349
• Classification
  • MicroRNA non-coding host genes
• VEGA ID
  OTTHUMG00000017195

Gene info

• Identity
  HGNC:8322
• Gene
  OR5B1P
• Long gene name
  olfactory receptor family 5 subfamily B member 1 pseudogene
• Synonyms gene
  • OR5B9P
  • OR5B9
  • OR5B5P
  • OR5B14P
  • OR5B7P
  • OR5B7
  • OR5B8
  • OR5B8P
  • OR5B5
  • OR5B6
  • OR5B6P
• Synonyms gene name
  • olfactory receptor, family 5, subfamily B, member 1 pseudogene
• Synonyms
  • OR8-122
  • OR8-123
  • OR6-57
  • OR6-55
  • OR3-144
  • OR912-92
• GenBank acession
  • U86283
• Locus
  11q12.1
• Discovery year
  1999-11-25
• Entrez gene record
  401692
• Pubmed identfication
  • 9500546
• Classification
  • Olfactory receptors, family 5
• VEGA ID
  OTTHUMG00000154286

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