Alternative names of antibody target:
BPIFF, Cholesteryl ester transfer protein, HDLCQ10, Lipid transfer protein I
Background information:
It has been proposed that high density lipoproteins (HDLs) function along with Lecithin, cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
This antibody reacts with:
Human, mouse, rat, rabbit
Immunogene sequence:
Recombinant CETP
Formulation of this antibody:
30 µg (0.5 mg/ml) polyclonal antibody in PBS pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Purification method:
Affinity Purified Antibody
Recommended usage:
Western Blot: 2-6 µg/ml
Identity 1869
Gene CETP
Long gene name cholesteryl ester transfer protein
Synonyms gene name- cholesteryl ester transfer protein, plasma
Synonyms name- BPI fold containing family F
Locus 16q13
Discovery year 2001-06-22
Entrez gene record 1071
Havana BLAST/BLAT OTTHUMG00000133279
