MLN-9708
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Catalog numberB2195-5
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PricePlease ask
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Size5 mg
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Alternative_name4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; ixazomib
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DescriptionMLN-9708 is a prodrug of Ixazomib citrate (MLN-2238). MLN-9708 is an orally bioavailable next-generation proteasome inhibitor (PI) with potential potent anticancer activity in both hematologic and solid tumor xenograft models with better pharmacokinetic and pharmacodynamic features than PS-341 (Cat. No. 1846).
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CAS Number1239908-20-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₀H₂₃BCl₂N₂O₉
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Molecular Weight517.12
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA next-generation proteasome inhibitor (PI)
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID56844015
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SMILESB1(OC(=O)C(O1)(CC(=O)O)CC(=O)O)C(CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl
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InChiInChI=1S/C20H23BCl2N2O9/c1-10(2)5-14(21-33-19(32)20(34-21,7-16(27)28)8-17(29)30)25-15(26)9-24-18(31)12-6-11(22)3-4-13(12)23/h3-4,6,10,14H,5,7-9H2,1-2H3,(H,24,31)(H,25,26)(H,27,28)(H,29,30)/t14-/m0/s1
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InChi KeyMBOMYENWWXQSNW-AWEZNQCLSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolMLN, MRLN
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Short nameMLN-9708
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Alternative nameMLN-9708
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Gene info
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Identity
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Gene
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Long gene namemotilin
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Synonyms name
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Locus
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Discovery year1988-08-05
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Entrez gene record
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Classification
- Neuropeptides
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemyoregulin
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Synonyms gene
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Synonyms gene name
- long intergenic non-protein coding RNA 948
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2013-06-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID