GSK-1059615

• Catalog number
  9450-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  5Z-​[[4-​(4-​pyridinyl)-​6-​quinolinyl]methylene]-​2,​4-​thiazolidinedione
• Description
  GSK-1059615 is a potent, reversible, ATP-competitive inhibitor of PI3Kα (IC₅₀ = 2 nM). It inhibits proliferation in BT474 cells and attenuates MAPK signaling.
• CAS Number
  958852-01-2
• Structure Available
  Yes
• Molecular Formula
  C₁₈H₁₁N₃O₂S
• Molecular Weight
  333.36
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~4 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, reversible PI3Kα inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD18074517
• PubChem CID
  23582824
• PubChem CID Link
• SMILES
  C1=CC2=NC=CC(=C2C=C1C=C3C(=O)NC(=O)S3)C4=CC=NC=C4
• InChi
  InChI=1S/C18H11N3O2S/c22-17-16(24-18(23)21-17)10-11-1-2-15-14(9-11)13(5-8-20-15)12-3-6-19-7-4-12/h1-10H,(H,21,22,23)/b16-10-
• InChi Key
  QDITZBLZQQZVEE-YBEGLDIGSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  GSK-1059615  
• Short name
  GSK-1059615
• Alternative name
  GSK-1059615

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