LDHAL6B Antibody (NT)
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Catalog number6737-100
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Price:
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Size100 μl
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Antibody TargetLDHAL6B
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Target Alternative NameLDHAL6B; LDHAL6; LDHL; L-lactate dehydrogenase A-like 6B
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Antibody TypePolyclonal
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Species ReactivitiesHuman.
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Immunogen SequenceThis LDHAL6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-71 amino acids from the N-terminal region of human LDHAL6B.
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AccessionQ9BYZ2
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Gene Id92483
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AppearanceColorless liquid
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FormLiquid
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Formulation100 µl of antibody in PBS with 0.09% (W/V) sodium azide
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PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
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ApplicationWestern blot.
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Positive ControlWestern blot: K562 cell line lysates
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Application And UsagesWestern blot: ~1:1000.
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DescriptionL-Lactate dehydrogenase A chain (LDHA) is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. Mutations in LDHA have been associated with in LDHA are the cause of glycogen storage disease type 11 (GSD11) which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolLDHAL6B
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Short nameLDHAL6B Antibody (NT)
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameLDHAL6B (antibody to-) (NT)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namelactate dehydrogenase A like 6B
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Synonyms gene
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Synonyms gene name
- lactate dehydrogenase A-like 6
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-06-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data