APG10/ATG10 Antibody

• Catalog number
  3910-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  APG10/ATG10
• Target Alternative Name
  APG10 , APG10L, ATG10 , DKFZP586I0418 , FLJ13954 , pp12616
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide, near the carboxyl terminus of human APG10
• Accession
  Q9H0Y0
• Gene Id
  84734
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  0.5 mg/ml affinity purified rabbit anti-APG10 in PBS containing 30% glycerol, 0.5 mg/ml BSA and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined.
• Description
  Autophagy, the process of bulk degradation of cellular proteins throμgh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) throμgh phosphorylation of autophagy protein APG1. Another member of the autophagy protein family is APG10 (Also called ATG10, APG10L), an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjμgation and the modification of a soluble form of MAP-LC3, a homolog of yeast Apg8, to a membrane-bound form. ATG10 has also been shown to interact with ATG12 in human embryonic kidney cells in the presence of ATG7. Multiple isoforms of ATG10 are known to exist.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  APG10/ATG10  
• Gene symbol
  ATG10-AS1, ATG10-IT1, ATG10
• Short name
  APG10/ATG10 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  APG10/ATG10 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40914
• Gene
  ATG10-AS1
• Long gene name
  ATG10 antisense RNA 1
• Synonyms gene name
  • ATG10 antisense RNA 1 (non-protein coding)
• Locus
  5q14.1
• Discovery year
  2011-05-19
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000162770

Gene info

• Identity
  HGNC:41455
• Gene
  ATG10-IT1
• Long gene name
  ATG10 intronic transcript 1
• Synonyms gene name
  • ATG10 intronic transcript 1 (non-protein coding)
• Locus
  5q14.1
• Discovery year
  2011-05-19
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000162771

Gene info

• Identity
  HGNC:20315
• Gene
  ATG10
• Long gene name
  autophagy related 10
• Synonyms gene
  • APG10L
• Synonyms gene name
  • APG10 autophagy 10-like (S. cerevisiae)
  • ATG10 autophagy related 10 homolog (S. cerevisiae)
• Synonyms
  • DKFZP586I0418
  • FLJ13954
• GenBank acession
  • AK024016
• Locus
  5q14.1-q14.2
• Discovery year
  2003-01-28
• Entrez gene record
  83734
• RefSeq identity
  • NM_001131028
• Classification
  • Autophagy related
• VEGA ID
  OTTHUMG00000119041

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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