Cyt387

• Catalog number
  2316-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-l)-benzamide; CYT11387
• Description
  Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC₅₀ values of 11 nM and 18 nM, respectively. Inhibits JAK3 at much higher concentrations (IC₅₀ = 155 nM).
• CAS Number
  1056634-68-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₂N₆O₂
• Molecular Weight
  414.46
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~80 mg/ml) or Ethanol (
• Handling
  Protect from air and light
• Tag Line
  A potent JAK1 and JAK2 inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD16038899
• PubChem CID
  25062766
• PubChem CID Link
• SMILES
  C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N
• InChi
  InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28)
• InChi Key
  ZVHNDZWQTBEVRY-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Cyt387  
• Short name
  Cyt387
• Alternative name
  Cyt387

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