Anti-Notch 1 (Cleaved-Val1744) Antibody

• Catalog number
  A1619-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  Notch 1
• Target Alternative Name
  AOS5; AOVD1; hN1; Lin-12; LIN12; Mis6; Motch A; mT14; Neurogenic locus notch homolog protein 1; Neurogenic locus notch protein homolog; NICD; NOTC1_HUMAN; Notch 1; Notch 1 intracellular domain; NOTCH; Notch gene homolog 1 (Drosophila); Notch homolog 1, translocation-associated (Drosophila); NOTCH, Drosophila, homolog of, 1; notch1; TAN1; Translocation associated notch homolog; Translocation associated notch protein TAN 1; Translocation-associated notch protein TAN-1; xotch
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Mouse, Rat
• Immunogen Sequence
  A synthesized peptide derived from human Notch 1 (Cleaved-Val1744)
• Accession
  P46531
• Gene Id
  4851
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  In phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol
• Purification
  Affinity purified
• Application
  WB, IHC, ELISA
• Positive Control
  WB: 3T3 cell extract, IHC: Mouse spleen tissue
• Application And Usages
  WB 1:500-1:2000 , IHC 1:50-1:200 , ELISA (peptide) 1:20000-1:40000
• Description
  Notch proteins are transmembrane receptor that regluate cell fate decisions. Four Notch homologs have been identified in mammals namely Notch 1, Notch 2, Notch 3 and Notch 4. The membrane ligand for Notch includes Jagged 1, Jagged 2 and Delta. Notch 1 is a 270 kDa transmembrane receptor that can be activated by Delta (Dl) ligand. Activation of Notch 1 will result in the proteolytic cleavage of Notch 1 into a 120 kDa length protein.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Notch   Cleaved-Val1744  
• Short name
  Anti-Notch 1 (Cleaved-Val1744) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toNotch 1 (Cleaved-Val1744) (antibody to-)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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